Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.49 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967210 | 0.85 | ALDH1A1 (0.55) | ERN1ALDH1A1TSHRTLR2TLR1 | |
| SCHEMBL19609001 | 0.82 | ALDH1A1 (0.61) | ERN1ALDH1A1TSHRMYCTRIM24 | |
| SCHEMBL172956 | 0.82 | ERN1 (0.61) | ERN1ALDH1A1TSHRTLR2TLR1 | |
| SCHEMBL29957719 | 0.82 | ERN1 (0.61) | ERN1ALDH1A1TSHRTLR2TLR1 | |
| SCHEMBL16439936 | 0.82 | ERN1 (0.67) | ERN1ALDH1A1TSHRTLR2TLR1 | |
| SCHEMBL31152506 | 0.82 | ERN1 (0.67) | ERN1ALDH1A1TSHRTLR2TLR1 | |
| SCHEMBL1666430 | 0.81 | ALDH1A1 (0.59) | ERN1ALDH1A1TSHRTLR2TLR1 | |
| SCHEMBL20339223 | 0.80 | ERN1 (0.59) | ERN1ALDH1A1TSHRTLR2TLR1 | |
| SCHEMBL3966538 | 0.80 | ERN1 (0.50) | ERN1ALDH1A1TSHRTLR2TLR1 | |
| SCHEMBL5734028 | 0.80 | ERN1 (0.46) | ERN1ALDH1A1TSHRTLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172351-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172351-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | GPR119, INSR, GLP1R | ERN1 2352/4885ALDH1A1 3930/4885TSHR 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.