SCHEMBL10012147

SCHEMBL10012147

Pc1ccc(C2CCCCC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
HDAC1 Q13547 1/20 0.44
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
NOTUM Q6P988 2/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
HSP90AA1 P07900 1/20 0.43
CYP11B2 P19099 1/20 0.42
HAO1 Q9UJM8 2/20 0.42
ESR2 Q92731 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GLA P06280 1/20 0.40
HIF1A Q16665 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ACMSD Q8TDX5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15260520 0.87 HDAC8 (0.52) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL28584923 0.87 HDAC8 (0.52) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL42782 0.87 HDAC8 (0.52) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL6275125 0.87 HDAC8 (0.52) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL5146632 0.84 ESR2 (0.52) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL781509 0.84 HDAC1 (0.54) HTTLMNAHDAC8HDAC6HDAC1
Hydrogen Peroxide SCHEMBL11391495 0.81 HAO1 (0.55) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL5147779 0.81 ESR2 (0.54) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL879500 0.80 HTT (0.44) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL59138 0.79 NOTUM (0.55) HTTLMNAHDAC8HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed