SCHEMBL10012784

SCHEMBL10012784

O=[C]c1ccc(C23CC4CC(CC(C4)C2)C3)cc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
ALDH1A1 P00352 2/20 0.57
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
RAB9A P51151 1/20 0.49
NPC1 O15118 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
EPHX2 P34913 4/20 0.47
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
PGR P06401 7/20 0.46
MAPT P10636 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.39
CASP2 P42575 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2763437 0.82 LMNA (0.77) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL419847 0.80 LMNA (0.57) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL4752577 0.80 PGR (0.68) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL10012162 0.80 LMNA (0.57) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL9250964 0.78 MEN1 (0.46) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL6684731 0.77 LMNA (0.53) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL5346553 0.77 LMNA (0.63) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL27865925 0.76 NPC1 (0.57) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL10012211 0.76 MEN1 (0.53) LMNAALDH1A1MEN1KMT2ARAB9A
SCHEMBL28803684 0.74 LMNA (0.50) LMNAALDH1A1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed