Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368529 | 0.84 | PGR (0.46) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7103212 | 0.84 | LMNA (0.45) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2763437 | 0.82 | LMNA (0.77) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL19089867 | 0.81 | PGR (0.40) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4752577 | 0.80 | PGR (0.68) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6698243 | 0.80 | LMNA (0.47) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10012162 | 0.80 | LMNA (0.57) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10012784 | 0.80 | LMNA (0.57) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6684731 | 0.77 | LMNA (0.53) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2763378 | 0.77 | PGR (0.55) | LMNAALDH1A1MEN1KMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920907-B | Aminated porous aromatic skeleton compound and preparation method and application thereof | 福建农林大学 | 2023-06-20 | — | — | CN | claimed |
| CN-114920907-A | Aminated porous aromatic skeleton compound and preparation method and application thereof | 福建农林大学 | 2022-08-19 | — | — | CN | claimed |
| CN-114618450-B | Conjugated microporous polymer composite material, preparation method thereof and adsorbent | 北京石墨烯技术研究院有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114618450-A | Conjugated microporous polymer composite material, preparation method thereof and adsorbent | 北京石墨烯技术研究院有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-114920907-B | Aminated porous aromatic skeleton compound and preparation method and application thereof | 福建农林大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-114920907-A | Aminated porous aromatic skeleton compound and preparation method and application thereof | 福建农林大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-114618450-B | Conjugated microporous polymer composite material, preparation method thereof and adsorbent | 北京石墨烯技术研究院有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114618450-A | Conjugated microporous polymer composite material, preparation method thereof and adsorbent | 北京石墨烯技术研究院有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-112961110-B | Olefin functionalized IPr HCl monomer and preparation method and application thereof | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-114168587-A | System and method for generating smell data and database thereof | 苏星 | 2022-03-11 | — | — | CN | disclosed |
| CN-112961110-A | Olefin functionalized IPr HCl monomer and preparation method and application thereof | 浙江工业大学 | 2021-06-15 | — | — | CN | disclosed |
| EP-2607348-B1 | Plasminogen Activator Inhibitor-1 Inhibitor | RENASCIENCE INC (JP) | 2021-03-17 | — | — | EP | disclosed |
| US-20140296256-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | RENASCIENCE CO LTD (JP) | 2014-10-02 | — | — | US | disclosed |
| US-8785473-B2 | Plasminogen activator inhibitor-1 inhibitor | RENASCIENCE CO., LTD. (JP) | 2014-07-22 | — | — | US | disclosed |
| EP-2607348-A2 | Plasminogen Activator Inhibitor-1 Inhibitor | Renascience CO., LTD. (JP) | 2013-06-26 | — | — | EP | disclosed |
| EP-2415755-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Renascience CO., LTD. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120022080-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | RENASCIENCE CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296256-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | SERPINE1, SERPINC1, SERPINB1 | LMNA 482/4885ALDH1A1 1450/4885MEN1 844/4885 |
| US-20120022080-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | LMNA 482/4885ALDH1A1 1450/4885MEN1 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.