SCHEMBL10012935

SCHEMBL10012935

CC(c1ccccc1)N(C=O)C(C)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.47
MTOR P42345 1/20 0.42
CYP2D6 P10635 2/20 0.39
CYP3A4 P08684 2/20 0.39
LMNA P02545 2/20 0.39
CHRM2 P08172 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
CHRM1 P11229 1/20 0.39
SMPD1 P17405 1/20 0.39
DRD1 P21728 1/20 0.39
TBXA2R P21731 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
OPRM1 P35372 1/20 0.39
DRD3 P35462 1/20 0.39
CASR P41180 1/20 0.39
HTR2B P41595 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11730270 0.80 ALOX5 (0.40) ALOX5MTORCYP2D6CYP3A4LMNA
SCHEMBL31061559 0.80 ALDH1A1 (0.47) ALOX5MTORCYP2D6LMNAHTR2A
SCHEMBL4310309 0.80 ALDH1A1 (0.47) ALOX5MTORCYP2D6LMNAHTR2A
SCHEMBL5949584 0.78 ALOX5 (0.53) ALOX5MTORCYP2D6TRPM8ALDH1A1
SCHEMBL7593804 0.78 ALOX5 (0.53) ALOX5MTORCYP2D6TRPM8ALDH1A1
SCHEMBL14394131 0.78 ALOX5 (0.48) ALOX5MTORLMNAADRA2ATRPM8
SCHEMBL155917 0.77 ALOX5 (0.43) ALOX5MTORCYP2D6LMNAHTR2A
SCHEMBL155916 0.77 ALOX5 (0.43) ALOX5MTORCYP2D6LMNAHTR2A
SCHEMBL16071108 0.72 HTR2A (0.44) ALOX5MTORLMNACHRM2CHRM1
SCHEMBL10010885 0.72 TRPM8 (0.43) CYP2D6LMNACYP2C19HTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed