SCHEMBL10012943

SCHEMBL10012943

[S]c1ccccc1C1C2CC3CC(C2)CC1C3

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.35
KMT2A Q03164 1/20 0.33
SCN9A Q15858 2/20 0.32
SIGMAR1 Q99720 1/20 0.32
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5672306 0.77 CYP3A4 (0.38) EPHX2SCN9ASIGMAR1
SCHEMBL28318181 0.75 KDM1A (0.47) KMT2A
SCHEMBL9721529 0.75 HTR2C (0.42) SIGMAR1
SCHEMBL28174692 0.75 SIGMAR1 (0.41) EPHX2SCN9ASIGMAR1CHRNB4CHRNA3
SCHEMBL5346555 0.75 EPHX2 (0.36) EPHX2KMT2ASCN9ASIGMAR1
SCHEMBL345589 0.75 HTR2A (0.42) EPHX2KMT2ASCN9A
SCHEMBL10012886 0.75 EPHX2 (0.33) EPHX2KMT2ASCN9ASIGMAR1
SCHEMBL10012163 0.75 EPHX2 (0.33) EPHX2KMT2ASCN9ASIGMAR1
SCHEMBL3629131 0.72 KDM1A (0.52)
SCHEMBL3921079 0.72 SCN9A (0.33) EPHX2SCN9ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed