SCHEMBL345589

SCHEMBL345589

Oc1ccccc1C1C2CC3CC(C2)CC1C3

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 2/20 0.36
ALOX15 P16050 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
CA12 O43570 1/20 0.36
GMNN O75496 1/20 0.36
ALDH1A1 P00352 1/20 0.36
EGFR P00533 1/20 0.36
CA2 P00918 1/20 0.36
LMNA P02545 1/20 0.36
FYN P06241 1/20 0.36
POLB P06746 1/20 0.36
CA3 P07451 1/20 0.36
CYP3A4 P08684 1/20 0.36
MMP9 P14780 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5365399 0.85 SMN1; SMN2 (0.38) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL2710155 0.82 G6PD (0.36) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL7745693 0.82 CHRNB2 (0.42) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL27797604 0.81 CHRNB2 (0.34) HTR2AHTR2CHTR2BEPHX2SCN9A
SCHEMBL15531515 0.81 TRPA1 (0.41) HTR2AHTR2CHTR2BMEN1KMT2A
SCHEMBL5672306 0.77 CYP3A4 (0.38) HTR2AHTR2CHTR2BALOX15ALDH1A1
SCHEMBL27520667 0.77 CHRNB2 (0.39) MEN1KMT2AMAPTALOX15KDM4E
SCHEMBL16046506 0.76 CHRNB2 (0.38) MEN1KMT2AALOX15ALDH1A1LMNA
SCHEMBL10012943 0.75 EPHX2 (0.35) KMT2AEPHX2SCN9A
SCHEMBL9721529 0.75 HTR2C (0.42) HTR2AHTR2CHTR2BALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181091-B Synthesis process of adamantane triphenylamine 维思普新材料(苏州)有限公司 2024-06-14 CN claimed
US-5851513-A Antiplaque oral composition and method COLGATE PALMOLIVE COMPANY (US) 1998-12-22 US claimed
CN-120192340-A Metal-containing film forming compound, metal-containing film forming composition, and pattern forming method 信越化学工业株式会社 2025-06-24 CN disclosed
CN-116694114-B Composition for forming metal oxide film, pattern forming method, and metal oxide film forming method 信越化学工业株式会社 2025-06-13 CN disclosed
CN-113050373-B Organic film forming material, organic film forming method, pattern forming method, and compound 信越化学工业株式会社 2025-05-16 CN disclosed
CN-113359390-B Composition for forming coated organic film, pattern forming method, polymer, and method for producing polymer 信越化学工业株式会社 2025-01-24 CN disclosed
CN-119087742-A Pattern forming method 信越化学工业株式会社 2024-12-06 CN disclosed
EP-3332783-B1 INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2024-12-04 EP disclosed
CN-118930452-A Organic film forming material, pattern forming method, and compound for organic film 信越化学工业株式会社 2024-11-12 CN disclosed
CN-112213919-B Composition for forming organic film, pattern forming method, and polymer 信越化学工业株式会社 2024-09-27 CN disclosed
CN-118676106-A Semiconductor device and method for manufacturing the same 旭化成株式会社 2024-09-20 CN disclosed
US-6780591-B2 POLYMERASE CHAIN REACTIONS ARIZONA BOARD OF REGENTS 2004-08-24 US disclosed
EP-1427851-A2 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES Arizona Board of Regents (US) 2004-06-16 EP disclosed
US-20030138809-A1 Method of determining the nucleotide sequence of oligonucleotides and DNA molecules HELICOS BIOSCIENCES CORPORATION 2003-07-24 US disclosed
WO-2003020895-A2 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES ARIZONA BOARD OF REGENTS (US) 2003-03-13 WO disclosed
US-20020137062-A1 Method of determining the nucleotide sequence of oligonucleotides and DNA molecules HELICOS BIOSCIENCES CORPORATION 2002-09-26 US disclosed
EP-1082458-A1 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES ARIZONA BOARD OF REGENTS (US) 2001-03-14 EP disclosed
WO-1999057321-A9 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES UNIV ARIZONA (US) 2000-02-17 WO disclosed
WO-1999057321-A1 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES ARIZONA BOARD OF REGENTS (US) 1999-11-11 WO disclosed
US-3883603-A Adamantyl-(1)-{62 -naphthol KAO CORP 1975-05-13 US disclosed