SCHEMBL10013033

SCHEMBL10013033

CC(C)Cn1c(S)nnc1-c1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
TSHR P16473 2/20 0.38
HSD11B1 P28845 1/20 0.38
KDM4E B2RXH2 3/20 0.38
LMNA P02545 3/20 0.38
APOBEC3G Q9HC16 2/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 2/20 0.38
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
GFER P55789 1/20 0.37
KMT2A Q03164 2/20 0.36
HTT P42858 2/20 0.36
MEN1 O00255 1/20 0.35
GLA P06280 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5335279 0.87 HPGD (0.44) ALDH1A1TSHRKDM4ELMNAAPOBEC3G
SCHEMBL12565565 0.84 SMN1; SMN2 (0.49) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL10011738 0.82 MEN1 (0.43) ALDH1A1TSHRHSD11B1KDM4EAPOBEC3G
SCHEMBL1543969 0.82 APOBEC3G (0.50) ALDH1A1TSHRHSD11B1KDM4ELMNA
SCHEMBL19604936 0.76 HSD11B1 (0.41) ALDH1A1TSHRHSD11B1KDM4ELMNA
SCHEMBL1104402 0.75 ALDH1A1 (0.55) ALDH1A1TSHRKDM4ELMNAHSD17B10
SCHEMBL5333289 0.74 SMN1; SMN2 (0.39) ALDH1A1TSHRKDM4ELMNAHSD17B10
SCHEMBL2883036 0.74 ALDH1A1 (0.36) ALDH1A1TSHRKDM4ELMNAAPOBEC3G
SCHEMBL1544137 0.73 HSD11B1 (0.56) ALDH1A1TSHRHSD11B1KDM4EHSD17B10
SCHEMBL1104358 0.72 TP53 (0.55) ALDH1A1TSHRHSD11B1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8753895-B2 Surface modified metal nano-particle and use thereof Postech Academy-Industries Foundation (KR) 2014-06-17 US disclosed
US-20130252274-A1 Surface Modified Metal Nano-Particle and Use Thereof POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2013-09-26 US disclosed
US-20120168681-A1 Surface Modified Metal Nano-Particle and Use Thereof POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2012-07-05 US disclosed