Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PLAU | P00749 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535150 | 0.74 | CYP1A2 (0.58) | CYP2C19CYP2D6CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL15478714 | 0.73 | PLAU (0.61) | CYP2C19CYP2D6CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL23783818 | 0.72 | CYP1A2 (0.56) | CYP2C19CYP2D6CYP2C9CYP1A2PLAU | |
| SCHEMBL16670764 | 0.70 | TSHR (0.63) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL2703372 | 0.70 | CYP1A2 (0.53) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL11262697 | 0.70 | CYP2D6 (0.53) | CYP2C19CYP2D6CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL29338499 | 0.70 | CYP1A2 (0.53) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| SCHEMBL27874722 | 0.69 | TSHR (0.60) | CYP2C19CYP2D6CYP2C9CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL28584054 | 0.68 | CYP2D6 (0.51) | CYP2C19CYP2D6CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL6695693 | 0.68 | TSHR (0.55) | CYP2C19CYP2D6CYP2C9CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10813934-B2 | Sirtuin modulators as inhibitors of cytomegalovirus | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| US-20160296523-A1 | Sirtuin Modulators as Inhibitors of Cytomegalovirus | THE TRUSTEES OF PRINCETON UNIVERSITY | 2016-10-13 | — | — | US | disclosed |
| US-20160296523-A1 | Sirtuin Modulators as Inhibitors of Cytomegalovirus | THE TRUSTEES OF PRINCETON UNIVERSITY | 2016-10-13 | — | — | US | disclosed |
| US-20120142750-A1 | INDOLEAMINE 2,3-DIOXYGENASE PATHWAYS IN THE GENERATION OF REGULATORY T CELLS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2012-06-07 | — | — | US | disclosed |
| US-20120142750-A1 | INDOLEAMINE 2,3-DIOXYGENASE PATHWAYS IN THE GENERATION OF REGULATORY T CELLS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2012-06-07 | — | — | US | disclosed |
| US-20090155311-A1 | INDOLEAMINE 2,3-DIOXYGENASE PATHWAYS IN THE GENERATION OF REGULATORY T CELLS | MED. COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155311-A1 | INDOLEAMINE 2,3-DIOXYGENASE PATHWAYS IN THE GENERATION OF REGULATORY T CELLS | MED. COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10813934-B2 | Sirtuin modulators as inhibitors of cytomegalovirus | SIRT1, SIRT2, SIRT7 | CYP2C19 4835/4885CYP2D6 4848/4885CYP2C9 4863/4885 |
| US-20160296523-A1 | Sirtuin Modulators as Inhibitors of Cytomegalovirus | SIRT1, SIRT2, SIRT7 | CYP2C19 4835/4885CYP2D6 4848/4885CYP2C9 4863/4885 |
| US-20090155311-A1 | INDOLEAMINE 2,3-DIOXYGENASE PATHWAYS IN THE GENERATION OF REGULATORY T CELLS | IDO2, IDO1, INMT | CYP2C19 1198/4885CYP2D6 294/4885CYP2C9 871/4885 |
| US-20120142750-A1 | INDOLEAMINE 2,3-DIOXYGENASE PATHWAYS IN THE GENERATION OF REGULATORY T CELLS | IDO2, IDO1, INMT | CYP2C19 1198/4885CYP2D6 294/4885CYP2C9 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.