Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567854 | 0.83 | TSHR (0.60) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1010680 | 0.80 | LMNA (0.64) | TSHRCYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL10013764 | 0.78 | CYP1A2 (0.78) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4453242 | 0.78 | ALDH1A1 (0.45) | LMNAAOC3MEN1KMT2AMAPK8 | |
| SCHEMBL6583793 | 0.78 | MEN1 (0.62) | LMNASMN1; SMN2TDP1AOC3MEN1 | |
| SCHEMBL13206752 | 0.76 | TSHR (0.56) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2404021 | 0.76 | SIGMAR1 (0.62) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28118170 | 0.76 | ATM (0.58) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2404187 | 0.75 | LMNA (0.52) | CYP1A2CYP3A4CYP2D6CYP2C19LMNA | |
| SCHEMBL710329 | 0.74 | LMNA (0.56) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | CONSEJO SUPERIOR DE (ES) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | BAX, BCL2, CASP3 | TSHR 4459/4885CYP1A2 2273/4885CYP3A4 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.