Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | BUB1 | O43683 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18487086 | 0.85 | L3MBTL1 (0.45) | L3MBTL1NOTUMBRD4CREBBPBUB1 | |
| SCHEMBL3836430 | 0.85 | L3MBTL1 (0.45) | L3MBTL1NOTUMBRD4CREBBPBUB1 | |
| SCHEMBL2878283 | 0.84 | SCN9A (0.44) | L3MBTL1FABP4NOTUMBRD4CREBBP | |
| SCHEMBL30763696 | 0.84 | NOTUM (0.63) | L3MBTL1NOTUMBRD4CREBBPBUB1 | |
| SCHEMBL29507058 | 0.84 | L3MBTL1 (0.44) | L3MBTL1NOTUMBRD4CREBBPBUB1 | |
| SCHEMBL1284244 | 0.84 | L3MBTL1 (0.44) | L3MBTL1NOTUMBRD4CREBBPBUB1 | |
| SCHEMBL3237691 | 0.84 | L3MBTL1 (0.44) | L3MBTL1NOTUMBRD4CREBBPBUB1 | |
| SCHEMBL2878376 | 0.84 | NOTUM (0.63) | L3MBTL1NOTUMBRD4CREBBPBUB1 | |
| SCHEMBL18788881 | 0.84 | L3MBTL1 (0.44) | L3MBTL1NOTUMBRD4CREBBPBUB1 | |
| SCHEMBL29507077 | 0.84 | L3MBTL1 (0.44) | L3MBTL1NOTUMBRD4CREBBPBUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118909047-A | SST as selective somatostatin5Cyclohexapeptides as receptor agonists | 奈克斯拉制药英国有限公司 | 2024-11-08 | — | — | CN | disclosed |
| US-11987648-B2 | Cyclohexapeptides as selective somatostatin SST5 receptor agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2024-05-21 | — | — | US | disclosed |
| US-20210363188-A1 | CYCLOHEXAPEPTIDES AS SELECTIVE SOMATOSTATIN SST5 RECEPTOR AGONISTS | NXERA PHARMA UK LIMITED (GB) | 2021-11-25 | — | — | US | disclosed |
| EP-3864026-A1 | CYCLOHEXAPEPTIDES AS SELECTIVE SOMATOSTATIN SST5 RECEPTOR AGONISTS | Heptares Therapeutics Limited (GB) | 2021-08-18 | — | — | EP | disclosed |
| CN-113195517-A | As selective somatostatin SST5Cyclohexapeptides of receptor agonists | 赫普泰雅治疗有限公司 | 2021-07-30 | — | — | CN | disclosed |
| EP-3466934-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2019-04-10 | — | — | EP | disclosed |
| US-10000450-B2 | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-06-19 | — | — | US | disclosed |
| US-10000450-B2 | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-06-19 | — | — | US | disclosed |
| US-20170166524-A1 | N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-06-15 | — | — | US | disclosed |
| US-20170166524-A1 | N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-06-15 | — | — | US | disclosed |
| US-8084442-B2 | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-12-27 | — | — | US | disclosed |
| WO-2011008725-A2 | METAL-CATALYZED CARBON-FLUORINE BOND FORMATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-01-20 | — | — | WO | disclosed |
| WO-2011008618-A1 | METAL-CATALYZED CARBON-FLUORINE BOND FORMATION | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2011-01-20 | — | — | WO | disclosed |
| EP-2066628-B1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI AVENTIS (FR) | 2010-10-20 | — | — | EP | disclosed |
| US-20090176804-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI-AVENTIS (FR) | 2009-07-09 | — | — | US | disclosed |
| EP-2066628-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Sanofi-Aventis (FR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008014186-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI-AVENTIS (FR) | 2008-01-31 | — | — | WO | disclosed |
| US-20070185121-A1 | Heterocyclyl-substituted dihydroquinazolines and their use as antiviral agents | BAYER HEALTHCARE AG (DE) | 2007-08-09 | — | — | US | disclosed |
| US-20070185121-A1 | Heterocyclyl-substituted dihydroquinazolines and their use as antiviral agents | BAYER HEALTHCARE AG (DE) | 2007-08-09 | — | — | US | disclosed |
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000450-B2 | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors | SLC6A2, TPH1, SLC6A3 | L3MBTL1 4596/4885FABP4 4042/4885NOTUM 2517/4885 |
| US-11987648-B2 | Cyclohexapeptides as selective somatostatin SST5 receptor agonists | SSTR5, SSTR1, SSTR3 | L3MBTL1 2068/4885FABP4 2399/4885NOTUM 4612/4885 |
| US-20170166524-A1 | N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS | SLC6A2, TPH1, SLC6A3 | L3MBTL1 4596/4885FABP4 4042/4885NOTUM 2517/4885 |
| US-20070185121-A1 | Heterocyclyl-substituted dihydroquinazolines and their use as antiviral agents | TYMP, RPL35, EIF2AK2 | L3MBTL1 4509/4885FABP4 4879/4885NOTUM 2547/4885 |
| US-20210363188-A1 | CYCLOHEXAPEPTIDES AS SELECTIVE SOMATOSTATIN SST5 RECEPTOR AGONISTS | SSTR5, SSTR1, SSTR3 | L3MBTL1 2068/4885FABP4 2399/4885NOTUM 4612/4885 |
| US-20090176804-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | PTGER2, PTGDR2, CYSLTR2 | L3MBTL1 3527/4885FABP4 3904/4885NOTUM 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.