SCHEMBL10013844

SCHEMBL10013844

COC(=O)C1(C)OC(C)C(C)O1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28382997 0.80 MEN1 (0.33) NPSR1
SCHEMBL15114572 0.80 MEN1 (0.33) NPSR1
SCHEMBL1073192 0.74 NPSR1 (0.37) NPSR1
SCHEMBL1075837 0.74 NPSR1 (0.34) NPSR1
SCHEMBL9692331 0.73
SCHEMBL28529459 0.73 LMNA (0.33)
SCHEMBL14507320 0.71 NPSR1 (0.31) NPSR1
SCHEMBL20054618 0.70 POLB (0.31)
SCHEMBL22141637 0.70 POLB (0.31)
SCHEMBL28381403 0.70 POLB (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108299374-B Fluorination process of perfluoro compound containing 1, 3-dioxolane ester or 1, 3-dioxane ester 博容新材料(深圳)有限公司 2020-01-03 CN claimed
CN-108299374-B Fluorination process of perfluoro compound containing 1, 3-dioxolane ester or 1, 3-dioxane ester 博容新材料(深圳)有限公司 2020-01-03 CN disclosed
US-8168808-B2 Fluorinated 1,3-dioxolane compounds, fluorinated polymers of the compounds, and optical or electrical materials comprising the polymers JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-05-01 US disclosed
EP-1658278-B1 METHOD FOR PRODUCING FLUORINATED 1,3-DIOXOLANE COMPOUNDS, FLUORINATED 1,3-DIOXOLANE COMPOUNDS, FLUORINATED POLYMERS OF THE FLUORINATED 1,3-DIOXOLANE COMPOUNDS, AND OPTICAL OR ELECTRICAL MATERIALS USING THE POLYMERS JAPAN SCIENCE & TECH AGENCY (JP) 2010-03-31 EP disclosed
US-20100056752-A1 Fluorinated 1,3-Dioxolane Compounds, Fluorinated Polymers of the Compounds, and Optical or Electrical Materials Comprising the Polymers JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2010-03-04 US disclosed
US-20100056752-A1 Fluorinated 1,3-Dioxolane Compounds, Fluorinated Polymers of the Compounds, and Optical or Electrical Materials Comprising the Polymers JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2010-03-04 US disclosed
US-7635780-B2 Method for producing fluorinated 1,3-dioxolane compounds, fluorinated 1, 3-dioxolane compounds, fluorinated polymers of the fluorinated 1,3-dioxolane compounds and optical or electrical materials using the polymers JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-12-22 US disclosed
US-20070043187-A1 Method for producing fluorinated 1,3-dioxolane compounds, fluorinated 1, 3-dioxolane compounds, fluorinated polymers of the fluorinated 1,3-dioxolane compounds and optical or electrical materials using the polymers JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043187-A1 Method for producing fluorinated 1,3-dioxolane compounds, fluorinated 1, 3-dioxolane compounds, fluorinated polymers of the fluorinated 1,3-dioxolane compounds and optical or electrical materials using the polymers RTF1, AFF1, AFF2 HTT 3573/4885NPSR1 2061/4885
US-20100056752-A1 Fluorinated 1,3-Dioxolane Compounds, Fluorinated Polymers of the Compounds, and Optical or Electrical Materials Comprising the Polymers RTF1, AFF4, AFF1 HTT 3547/4885NPSR1 2157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.