Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 5/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | CFTR | P13569 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20256014 | 0.86 | USP2 (0.55) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL21648586 | 0.84 | ABCB1 (0.66) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL12827098 | 0.84 | ABCB1 (0.63) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL7907876 | 0.83 | ABCB1 (0.71) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL26774230 | 0.83 | ABCB1 (0.52) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL16425659 | 0.82 | ABCB1 (0.63) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL21648583 | 0.82 | ABCB1 (0.63) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL12747272 | 0.82 | ABCB1 (0.66) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL458205 | 0.81 | ABCB1 (0.77) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL4567588 | 0.80 | ABCB1 (0.60) | ABCB1USP2ATMCFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49518-E1 | Fluorescent probe for detecting calpain activity | THE UNIVERSITY OF TOKYO (JP) | 2023-05-02 | — | — | US | disclosed |
| US-RE49518-E1 | Fluorescent probe for detecting calpain activity | THE UNIVERSITY OF TOKYO (JP) | 2023-05-02 | — | — | US | disclosed |
| WO-2022270607-A1 | FLUORESCENT PROBES | 株式会社 東北テクノアーチ | 2022-12-29 | — | — | WO | disclosed |
| US-10294240-B2 | Fluorescent probe for detecting calpain activity | THE UNIVERSITY OF TOKYO (JP) | 2019-05-21 | — | — | US | disclosed |
| US-20180162871-A1 | FLUORESCENT PROBE FOR DETECTING CALPAIN ACTIVITY | THE UNIVERSITY OF TOKYO (JP) | 2018-06-14 | — | — | US | disclosed |
| US-9610366-B2 | Method for diagnosing cancer | THE UNIVERSITY OF TOKYO (JP) | 2017-04-04 | — | — | US | disclosed |
| US-9610366-B2 | Method for diagnosing cancer | THE UNIVERSITY OF TOKYO (JP) | 2017-04-04 | — | — | US | disclosed |
| US-9506102-B2 | Fluorescent probe for high-sensitivity pancreatic fluid detection, and method for detecting pancreatic fluid | THE UNIVERSITY OF TOKYO (JP) | 2016-11-29 | — | — | US | disclosed |
| US-9506102-B2 | Fluorescent probe for high-sensitivity pancreatic fluid detection, and method for detecting pancreatic fluid | THE UNIVERSITY OF TOKYO (JP) | 2016-11-29 | — | — | US | disclosed |
| EP-2399920-B1 | FLUORESCENT PROBE FOR USE IN MEASUREMENT OF PROTEASE | UNIV TOKYO (JP) | 2015-03-25 | — | — | EP | disclosed |
| US-20140206992-A1 | METHOD FOR DIAGNOSING CANCER | THE UNIVERSITY OF TOKYO (JP) | 2014-07-24 | — | — | US | disclosed |
| US-20140206992-A1 | METHOD FOR DIAGNOSING CANCER | THE UNIVERSITY OF TOKYO (JP) | 2014-07-24 | — | — | US | disclosed |
| US-8461358-B2 | Fluorescent probe for measuring protease | THE UNIVERSITY OF TOKYO (JP) | 2013-06-11 | — | — | US | disclosed |
| US-8461358-B2 | Fluorescent probe for measuring protease | THE UNIVERSITY OF TOKYO (JP) | 2013-06-11 | — | — | US | disclosed |
| US-20130023675-A1 | DIAGNOSTIC FOR CANCER | THE UNIVERSITY OF TOKYO (JP) | 2013-01-24 | — | — | US | disclosed |
| US-20130023675-A1 | DIAGNOSTIC FOR CANCER | THE UNIVERSITY OF TOKYO (JP) | 2013-01-24 | — | — | US | disclosed |
| US-20120052518-A1 | FLUORESCENT PROBE FOR MEASURING PROTEASE | THE UNIVERSITY OF TOKYO (JP) | 2012-03-01 | — | — | US | disclosed |
| EP-2399920-A1 | FLUORESCENT PROBE FOR USE IN MEASUREMENT OF PROTEASE | The University of Tokyo (JP) | 2011-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162871-A1 | FLUORESCENT PROBE FOR DETECTING CALPAIN ACTIVITY | CAPN1, CAPNS1, CAPN2 | ABCB1 1972/4885USP2 1179/4885ATM 3862/4885 |
| US-20130023675-A1 | DIAGNOSTIC FOR CANCER | CDC73, BRCA1, HNRNPH3 | ABCB1 1208/4885USP2 2138/4885ATM 1655/4885 |
| US-20140206992-A1 | METHOD FOR DIAGNOSING CANCER | H1-3, H1-10, C1R | ABCB1 1447/4885USP2 1817/4885ATM 2217/4885 |
| US-20120052518-A1 | FLUORESCENT PROBE FOR MEASURING PROTEASE | CTRL, PRSS3, PRSS1 | ABCB1 2822/4885USP2 733/4885ATM 4637/4885 |
| US-10294240-B2 | Fluorescent probe for detecting calpain activity | CAPN1, CAPNS1, CAPN2 | ABCB1 1972/4885USP2 1179/4885ATM 3862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.