Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | PLEC | Q15149 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14433567 | 0.87 | MEN1 (0.68) | USP2L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL10013899 | 0.86 | ABCB1 (0.62) | USP2L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL15483658 | 0.86 | USP2 (0.51) | USP2L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL20362457 | 0.83 | KDM4E (0.50) | USP2L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL15483870 | 0.81 | ALDH1A1 (0.47) | USP2L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL29707441 | 0.81 | ALDH1A1 (0.47) | USP2L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL3430200 | 0.81 | USP2 (0.74) | USP2L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL7970133 | 0.81 | USP2 (0.54) | USP2L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL10021384 | 0.80 | USP2 (0.45) | USP2L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL24418686 | 0.79 | AR (0.45) | USP2L3MBTL1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294240-B2 | Fluorescent probe for detecting calpain activity | THE UNIVERSITY OF TOKYO (JP) | 2019-05-21 | — | — | US | disclosed |
| US-20180162871-A1 | FLUORESCENT PROBE FOR DETECTING CALPAIN ACTIVITY | THE UNIVERSITY OF TOKYO (JP) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162871-A1 | FLUORESCENT PROBE FOR DETECTING CALPAIN ACTIVITY | CAPN1, CAPNS1, CAPN2 | USP2 1179/4885L3MBTL1 2924/4885KMT2A 4420/4885 |
| US-10294240-B2 | Fluorescent probe for detecting calpain activity | CAPN1, CAPNS1, CAPN2 | USP2 1179/4885L3MBTL1 2924/4885KMT2A 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.