SCHEMBL458205

SCHEMBL458205

N=c1ccc2c(-c3ccccc3C(=O)O)c3ccc(N)cc3oc-2c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.77
USP2 O75604 5/20 0.74
ATM Q13315 2/20 0.74
CFTR P13569 1/20 0.74
PAX8 Q06710 1/20 0.74
GOPC Q9HD26 1/20 0.74
L3MBTL1 Q9Y468 1/20 0.57
FTO Q9C0B1 2/20 0.46
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
POLB P06746 3/20 0.43
ALPL P05186 1/20 0.43
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43
GNG2 P59768 1/20 0.42
GNB1 P62873 1/20 0.42
KDM4E B2RXH2 3/20 0.41
THRB P10828 2/20 0.41
HTT P42858 2/20 0.41
RECQL P46063 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5606345 0.99 USP2 (0.76) ABCB1USP2ATMCFTRPAX8
Hydrochloric Acid SCHEMBL29376502 0.99 USP2 (0.76) ABCB1USP2ATMCFTRPAX8
Sulfuric Acid SCHEMBL16593429 0.96 ABCB1 (0.71) ABCB1USP2ATMCFTRPAX8
Sulfuric Acid SCHEMBL16593427 0.93 ABCB1 (0.68) ABCB1USP2ATMCFTRPAX8
SCHEMBL23309754 0.90 ABCB1 (0.76) ABCB1USP2ATMCFTRPAX8
SCHEMBL9979456 0.90 ABCB1 (0.79) ABCB1USP2ATMCFTRPAX8
SCHEMBL14693687 0.90 ABCB1 (0.76) ABCB1USP2ATMCFTRPAX8
SCHEMBL29483446 0.88 ABCB1 (0.63) ABCB1USP2ATMCFTRPAX8
SCHEMBL14627720 0.88 ABCB1 (0.63) ABCB1USP2ATMCFTRPAX8
SCHEMBL3430200 0.87 USP2 (0.74) ABCB1USP2ATMCFTRPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010045529-A1 Double-resonance-absorption microscope OLYMPUS CORPORATION (JP) 2001-11-29 US claimed
EP-4714951-A1 FLUORESCENT DYE, SYNTHESIS THEREFOR AND USE THEREOF MGI Tech Co., Ltd. (CN) 2026-03-25 EP disclosed
US-12379375-B2 Methods for assessing cell surface glycosylation JUNO THERAPEUTICS, INC. (US) 2025-08-05 US disclosed
WO-2024240051-A1 FLUORESCENT DYE, SYNTHESIS THEREFOR AND USE THEREOF 深圳华大智造科技股份有限公司 2024-11-28 WO disclosed
US-20240159743-A1 METHODS FOR ASSESSING CELL SURFACE GLYCOSYLATION JUNO THERAPEUTICS, INC. (US) 2024-05-16 US disclosed
WO-2023219136-A1 FLUORESCENT PROBE FOR DETECTING PEPTIDE-LINKED HYDROLASE 国立大学法人 東京大学 2023-11-16 WO disclosed
US-11796534-B2 Methods for assessing cell surface glycosylation JUNO THERAPEUTICS, INC. (US) 2023-10-24 US disclosed
US-11753431-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2023-09-12 US disclosed
US-11753431-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2023-09-12 US disclosed
WO-2023125530-A1 ANTIBODY DRUG CONJUGATES BEIGENE, LTD. (KY) 2023-07-06 WO disclosed
US-20060088507-A1 Rhodamine derivatives for photodynamic diagnosis and treatment UNIVERSITE DE MONTREAL (CA) 2006-04-27 US disclosed
US-6844963-B2 Double-resonance-absorption microscope OLYMPUS OPTICAL CO., LTD. (JP) 2005-01-18 US disclosed
US-6667830-B1 Super-resolution microscope system and method for illumination JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-12-23 US disclosed
EP-1267931-A1 RHODAMINE DERIVATIVES FOR PHOTODYNAMIC DIAGNOSIS AND TREATMENT UNIVERSITE DE MONTREAL (CA) 2003-01-02 EP disclosed
EP-1228152-A1 METHOD FOR PRODUCING A WOOD COATING AGENT Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2002-08-07 EP disclosed
US-20010045529-A1 Double-resonance-absorption microscope OLYMPUS CORPORATION (JP) 2001-11-29 US disclosed
WO-2001024824-A1 RHODAMINE DERIVATIVES FOR PHOTODYNAMIC DIAGNOSIS AND TREATMENT UNIVERSITE DE MONTREAL (CA) 2001-04-12 WO disclosed
WO-2001018131-A1 METHOD FOR PRODUCING A WOOD COATING AGENT Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2001-03-15 WO disclosed
WO-1990015441-A1 LASER DYE LIQUIDS, LASER DYE INSTRUMENTS AND METHODS EXCITON INCORPORATED (US) 1990-12-13 WO disclosed
US-4896329-A Laser dye liquids, laser dye instruments and methods EXCITON INCORPORATED (US) 1990-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11753431-B2 Compounds comprising cleavable linker and uses thereof VIP, ANTXR2, TNFRSF9 ABCB1 2383/4885USP2 2521/4885ATM 2889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.