SCHEMBL1001398

SCHEMBL1001398

C=CS(=O)(=O)C(=O)[C@@H](N)CC(N)=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5490658 0.76 SLC7A5 (0.48)
SCHEMBL8368378 0.76 SLC7A5 (0.48)
SCHEMBL8365781 0.71 RNPEP (0.35) CA1CA2
SCHEMBL8365782 0.71 RNPEP (0.35) CA1CA2
SCHEMBL9636832 0.69 MEN1 (0.30)
SCHEMBL10972597 0.68 MAPT (0.42)
SCHEMBL2515415 0.68 MAPT (0.42)
Asparagine SCHEMBL27637754 0.67 GRIK1 (0.48)
Asparagine SCHEMBL27637755 0.67 GRIK1 (0.48)
SCHEMBL8336395 0.67 ALDH1A1 (0.42) CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2467144-A1 COMBINATION OF PROTEASOME INHIBITORS AND ANTI-HEPATITIS MEDICATION FOR TREATING HEPATITIS ViroLogik GmbH (DE) 2012-06-27 EP claimed
WO-2011009961-A1 COMBINATION OF PROTEASOME INHIBITORS AND ANTI-HEPATITIS MEDICATION FOR TREATING HEPATITIS VIROLOGIK GMBH (DE) 2011-01-27 WO claimed