Asparagine

Asparagine

SCHEMBL27637754

C=CC(N)=O.NC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 13/20 0.48
GRIK2 Q13002 9/20 0.48
GRM1 Q13255 1/20 0.48
GRM2 Q14416 1/20 0.48
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
FGFR4 P22455 1/20 0.48
ALOX15 P16050 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
KMT2A Q03164 1/20 0.45
SLC7A5 Q01650 1/20 0.41
GRIA2 P42262 2/20 0.41
GRIA4 P48058 2/20 0.41
GRIK3 Q13003 2/20 0.41
GRIK5 Q16478 2/20 0.41
GRIA1 P42261 1/20 0.41
PTGS1 P23219 1/20 0.39
SLC7A11 Q9UPY5 1/20 0.39
GGT1 P19440 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL27637755 1.00 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2ALDH1A1
D-Aspartate SCHEMBL30284873 0.87 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2ALDH1A1
Asparagine SCHEMBL4347082 0.86 ALOX15 (0.56) GRIK1GRIK2GRM1GRM2ALOX15
Asparagine SCHEMBL8826 0.86
Asparagine SCHEMBL30131205 0.86
Asparagine SCHEMBL288093 0.86 ALOX15 (0.56) GRIK1GRIK2GRM1GRM2ALOX15
Asparagine SCHEMBL288094 0.86 ALOX15 (0.56) GRIK1GRIK2GRM1GRM2ALOX15
Asparagine SCHEMBL150535 0.86 ALOX15 (0.56) GRIK1GRIK2GRM1GRM2ALOX15
Asparagine SCHEMBL20489207 0.86 ALOX15 (0.56) GRIK1GRIK2GRM1GRM2ALOX15
Asparagine SCHEMBL15460 0.86 ALOX15 (0.56) GRIK1GRIK2GRM1GRM2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1812726-B Method for reducing acrylamide in corn-based foods, corn-based foods with reduced levels of acrylamide, and articles of commerce PROCTER & GAMBLE 2010-06-09 CN disclosed
CN-100594802-C Method for reducing acrylamide formation in thermally processed foods FRITO LAY NORTH AMERICA INC 2010-03-24 CN disclosed
CN-101631475-A Method for reducing acrylamide formation FRITO LAY NORTH AMERICA INC 2010-01-20 CN disclosed
CN-1812726-A Method for reducing acrylamide in corn-based foods, corn-based foods with reduced levels of acrylamide, and articles of commerce PROCTER & GAMBLE (US) 2006-08-02 CN disclosed
CN-1753622-A Method for reducing acrylamide formation in thermally processed foods FRITO LAY NORTH AMERICA INC (US) 2006-03-29 CN disclosed