SCHEMBL10014356

SCHEMBL10014356

COC1OC(C(=O)O)C(O)C(OC2OC(CO)C(O)C(O)C2O)C1O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 7/20 0.52
▸ LGALS3 P17931 2/20 0.45
▸ LGALS9 O00182 1/20 0.45
▸ LGALS1 P09382 1/20 0.45
▸ LGALS7; LGALS7B P47929 1/20 0.45
▸ IGF2R P11717 1/20 0.45
▸ FGF1 P05230 2/20 0.44
▸ FGF2 P09038 1/20 0.44
▸ VEGFA P15692 1/20 0.44
▸ HPSE Q9Y251 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ CD209 Q9NNX6 1/20 0.41
▸ LGALS4 P56470 1/20 0.41
▸ PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17087678 0.95 LGALS8 (0.55) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL13559836 0.92 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL13867741 0.92 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL13288201 0.92 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL13560177 0.92 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL14255515 0.92 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL13559835 0.92 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL13560166 0.92 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL10014361 0.91 LGALS8 (0.45) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL10014359 0.90 IGF2R (0.50) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9289443-B2 Pharmaceutical composition and method for preventing or treating hepatitis C INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2016-03-22 — — US disclosed
US-9289443-B2 Pharmaceutical composition and method for preventing or treating hepatitis C INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2016-03-22 — — US disclosed
US-20120165279-A1 PHARMACEUTICAL COMPOSITION AND METHOD FOR PREVENTING OR TREATING HEPATITIS C INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-06-28 — — US disclosed
US-20120165279-A1 PHARMACEUTICAL COMPOSITION AND METHOD FOR PREVENTING OR TREATING HEPATITIS C INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-06-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165279-A1 PHARMACEUTICAL COMPOSITION AND METHOD FOR PREVENTING OR TREATING HEPATITIS C LIPC, HAVCR2, LIPA LGALS8 1603/4885LGALS3 1079/4885LGALS9 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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