Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.47 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.47 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.47 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.47 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.47 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30076250 | 0.81 | KDM1A (0.48) | AKR1C3AKR1C2CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL29279322 | 0.80 | KDM1A (0.49) | AKR1C3AKR1C2CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL10014734 | 0.80 | AKR1C3 (0.47) | AKR1C3AKR1C2RPS6KA3ACHEMAOB | |
| SCHEMBL18970766 | 0.80 | GRIN1 (0.42) | CLK4ACHE | |
| SCHEMBL16806016 | 0.79 | CYP1A1 (0.54) | AKR1C3AKR1C2CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL10014743 | 0.79 | AKR1C3 (0.45) | AKR1C3AKR1C2CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL24061160 | 0.79 | ACHE (0.53) | AKR1C3AKR1C2CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL3731784 | 0.77 | KDM1A (0.53) | AKR1C3AKR1C2CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL14118224 | 0.77 | CD274 (0.60) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL28189326 | 0.77 | CYP1A2 (0.54) | AKR1C3AKR1C2CYP1A1CYP1A2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | SOLVAY SA (BE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | PPIP5K2, HPRT1, PHPT1 | AKR1C3 3856/4885AKR1C2 4199/4885CYP1A1 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.