Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.43 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.43 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.43 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.43 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10014736 | 0.81 | AKR1C3 (0.42) | AKR1C3AKR1C2RPS6KA3CLK4DYRK1A | |
| SCHEMBL10014741 | 0.79 | AKR1C3 (0.49) | AKR1C3AKR1C2KDM1AKDM1BCYP1A2 | |
| SCHEMBL10014728 | 0.77 | HSD17B14 (0.36) | ALDH1A1BRD4HSD17B10 | |
| SCHEMBL12750060 | 0.75 | CCR1 (0.50) | KDM1ACYP17A1CYP11B1CYP11B2 | |
| SCHEMBL10014739 | 0.72 | AKR1C3 (0.58) | AKR1C3AKR1C2KDM1AKDM1BCYP1A2 | |
| SCHEMBL29279322 | 0.72 | KDM1A (0.49) | AKR1C3AKR1C2KDM1AKDM1BCYP1A2 | |
| SCHEMBL28189326 | 0.72 | CYP1A2 (0.54) | AKR1C3AKR1C2KDM1AKDM1BCYP1A2 | |
| SCHEMBL24330236 | 0.72 | TDO2 (0.49) | AKR1C3AKR1C2KDM1AKDM1BCYP1A2 | |
| SCHEMBL21586175 | 0.72 | CYP1A1 (0.46) | AKR1C3AKR1C2KDM1AKDM1BCYP1A2 | |
| SCHEMBL30516664 | 0.72 | CASR (0.58) | AKR1C3AKR1C2KDM1AKDM1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | SOLVAY SA (BE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | PPIP5K2, HPRT1, PHPT1 | AKR1C3 3856/4885AKR1C2 4199/4885KDM1A 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.