SCHEMBL10014830

SCHEMBL10014830

CCO[Si](C)(C)CCCNC(=O)CC(=O)NCCC[Si](C)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CASP2 P42575 1/20 0.33
FAAH O00519 3/20 0.33
TSHR P16473 2/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
NAAA Q02083 1/20 0.32
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
RECQL P46063 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
ACHE P22303 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4879743 0.85 MEN1 (0.39) MEN1KMT2ACASP2FAAHTSHR
SCHEMBL4885721 0.83 MEN1 (0.41) MEN1KMT2ACASP2FAAHTSHR
SCHEMBL16422222 0.83 MEN1 (0.41) MEN1KMT2ACASP2FAAHTSHR
SCHEMBL10018607 0.83 ACHE (0.41) ACHEEPHX1
SCHEMBL2566017 0.80 EPHX1 (0.47) MEN1KMT2ATSHRCA12CA1
SCHEMBL2626787 0.80 TSHR (0.40) MEN1KMT2ACASP2FAAHTSHR
SCHEMBL2616729 0.79 KDM4E (0.50) MEN1KMT2ATSHRCA12CA1
SCHEMBL23289097 0.79 EPHX2 (0.40) MEN1KMT2ACASP2FAAHTSHR
SCHEMBL960960 0.79 NAAA (0.45) MEN1KMT2ACASP2FAAHTSHR
SCHEMBL10002243 0.79 NAAA (0.45) MEN1KMT2ACASP2FAAHTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9442431-B2 Intermediate transfer member, imaging apparatus, and method EASTMAN KODAK COMPANY (US) 2016-09-13 US disclosed
US-20120301176-A1 ELECTROSTATOGRAPHIC CLEANING BLADE MEMBER AND APPARATUS BANK OF AMERICA, N.A., AS AGENT 2012-11-29 US disclosed
US-20120171494-A1 INTERMEDIATE TRANSFER MEMBER, IMAGING APPARATUS, AND METHOD BANK OF AMERICA, N.A., AS AGENT 2012-07-05 US disclosed
US-8170441-B2 Cleaning blade for electrostatographic apparatus EASTMAN KODAK COMPANY (US) 2012-05-01 US disclosed
US-20110211883-A1 CLEANING BLADE FOR ELECTROSTATOGRAPHIC APPARATUS BANK OF AMERICA, N.A., AS AGENT 2011-09-01 US disclosed