SCHEMBL10018607

SCHEMBL10018607

CCO[Si](C)(C)CCCNC(=O)OCOC(=O)NCCC[Si](C)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.41
EPHX1 P07099 1/20 0.34
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
NCOR2 Q9Y618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916622 0.85 ACHE (0.47) ACHEEPHX1HDAC3HDAC4HDAC1
SCHEMBL10014830 0.83 MEN1 (0.38) ACHEEPHX1
SCHEMBL14129111 0.81 ACHE (0.36) ACHEHDAC3HDAC4HDAC1HDAC7
SCHEMBL5916808 0.81 ACHE (0.46) ACHEEPHX1HDAC3HDAC4HDAC1
SCHEMBL19075901 0.81 L3MBTL1 (0.41) ACHEEPHX1
SCHEMBL5916701 0.80 EPHX1 (0.53) ACHEEPHX1
SCHEMBL13978964 0.80 ACHE (0.69) ACHEEPHX1
SCHEMBL5916593 0.80 ACHE (0.46) ACHEEPHX1HDAC3HDAC4HDAC1
SCHEMBL7572210 0.80 ACHE (0.46) ACHEEPHX1HDAC3HDAC4HDAC1
SCHEMBL10002240 0.79 ACHE (0.56) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475926-B2 Intermediate transfer member and imaging apparatus and method EASTMAN KODAK COMPANY (US) 2013-07-02 US disclosed
US-20120107559-A1 INTERMEDIATE TRANSFER MEMBER AND IMAGING APPARATUS AND METHOD KODAK (NEAR EAST) INC. 2012-05-03 US disclosed