SCHEMBL10015033

SCHEMBL10015033

CC1(C)OB(c2cc3c4ccccc4c(B4OC(C)(C)C(C)(C)O4)cc3c3ccccc23)OC1(C)C

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LPL P06858 12/20 0.44
LIPG Q9Y5X9 12/20 0.44
ANPEP P15144 1/20 0.36
LAP3 P28838 1/20 0.36
EGFR P00533 1/20 0.33
JAK2 O60674 1/20 0.33
BTK Q06187 1/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
P4HB P07237 1/20 0.33
P2RX7 Q99572 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20623676 0.91 LPL (0.41) LPLLIPGANPEPLAP3EGFR
SCHEMBL30428819 0.91 LPL (0.41) LPLLIPGANPEPLAP3EGFR
SCHEMBL2228172 0.90 HPRT1 (0.45) LPLLIPG
SCHEMBL31357522 0.90 HPRT1 (0.45) LPLLIPG
SCHEMBL734336 0.87 LPL (0.45) LPLLIPGANPEPLAP3
SCHEMBL22433031 0.85 LPL (0.40) LPLLIPGANPEPLAP3EGFR
SCHEMBL31277382 0.85 LPL (0.40) LPLLIPGANPEPLAP3EGFR
SCHEMBL2027186 0.85 LPL (0.48) LPLLIPGANPEPLAP3JAK2
SCHEMBL17120265 0.84 LPL (0.38) LPLLIPGEGFRPRMT5WDR77
SCHEMBL12200520 0.84 LPL (0.34) LPLLIPGEGFRJAK2BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120013700-A1 NOVEL FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-01-19 US disclosed
US-20120013700-A1 NOVEL FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-01-19 US disclosed
US-20110315973-A1 NOVEL FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-12-29 US disclosed
US-20110315973-A1 NOVEL FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-12-29 US disclosed
US-20110147731-A1 CONDENSED RING AROMATIC COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-06-23 US disclosed
US-20110147731-A1 CONDENSED RING AROMATIC COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-06-23 US disclosed
US-7919198-B2 Condensed ring aromatic compound for organic light-emitting device and organic light-emitting device having the same CANON KABUSHIKI KAISHA (JP) 2011-04-05 US disclosed
US-7919198-B2 Condensed ring aromatic compound for organic light-emitting device and organic light-emitting device having the same CANON KABUSHIKI KAISHA (JP) 2011-04-05 US disclosed
US-20100327274-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2010-12-30 US disclosed
US-20100327274-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2010-12-30 US disclosed
WO-2010116661-A1 NOVEL FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2010-10-14 WO disclosed
US-20100026171-A1 CONDENSED RING AROMATIC COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2010-02-04 US disclosed
US-20100026171-A1 CONDENSED RING AROMATIC COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2010-02-04 US disclosed
WO-2009123344-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110315973-A1 NOVEL FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE NR2E3, PYM1, TYR LPL 2431/4885LIPG 3493/4885ANPEP 3971/4885
US-20100026171-A1 CONDENSED RING AROMATIC COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME TYR, AHR, CRY1 LPL 3376/4885LIPG 3954/4885ANPEP 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.