SCHEMBL2228172

SCHEMBL2228172

CC1(C)OB(c2cc3c4ccccc4ccc3c3ccccc23)OC1(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.45
LPL P06858 2/20 0.45
LIPG Q9Y5X9 2/20 0.45
ALDH1A1 P00352 5/20 0.39
HSD17B10 Q99714 3/20 0.39
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1B1 Q16678 2/20 0.38
HIF1A Q16665 1/20 0.38
CYP1A2 P05177 5/20 0.38
FYN P06241 2/20 0.38
ACHE P22303 2/20 0.38
AHR P35869 2/20 0.38
MAPT P10636 2/20 0.38
LCK P06239 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
SLC6A2 P23975 1/20 0.38
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31357522 1.00 HPRT1 (0.45) HPRT1LPLLIPGALDH1A1HSD17B10
SCHEMBL10015033 0.90 LPL (0.44) LPLLIPG
SCHEMBL476903 0.89 HPRT1 (0.47) HPRT1LPLLIPGALDH1A1HSD17B10
SCHEMBL24951376 0.89 HPRT1 (0.47) HPRT1LPLLIPGALDH1A1HSD17B10
SCHEMBL734336 0.88 LPL (0.45) HPRT1LPLLIPGALDH1A1HSD17B10
SCHEMBL17120286 0.87 LPL (0.40) HPRT1LPLLIPGALDH1A1HSD17B10
SCHEMBL31730284 0.86 LPL (0.40) HPRT1LPLLIPGALDH1A1HSD17B10
SCHEMBL17120265 0.85 LPL (0.38) LPLLIPGALDH1A1HSD17B10TSHR
SCHEMBL18164776 0.85 KMT2A (0.42) LPLLIPGALDH1A1HSD17B10TSHR
SCHEMBL25668940 0.84 HPRT1 (0.42) HPRT1LPLLIPGALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12167689-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-12-10 US disclosed
US-11903311-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-02-13 US disclosed
US-20230140609-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed
US-20230140609-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed
US-20220336757-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2022-10-20 US disclosed
EP-3480194-B1 HETEROCYCLIC COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES USING SAME LG CHEMICAL LTD (KR) 2021-09-08 EP disclosed
EP-3480194-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG Chem, Ltd. (KR) 2019-05-08 EP disclosed
US-20180337348-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2018-11-22 US disclosed
US-9362506-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-07 US disclosed
US-9362506-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-07 US disclosed
US-20100117526-A1 NOVEL AZAINDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2010-05-13 US disclosed
US-20100117526-A1 NOVEL AZAINDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2010-05-13 US disclosed
WO-2009139499-A1 DIBENZO[c,g]FLUORENE COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-11-19 WO disclosed
US-20090278447-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2009-11-12 US disclosed
EP-2049616-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[K]FLUORANTHENE COMPOUND Canon Kabushiki Kaisha (JP) 2009-04-22 EP disclosed
US-20090079331-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-03-26 US disclosed
US-20090079331-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-03-26 US disclosed
US-20090033210-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-02-05 US disclosed
US-20080286611-A1 BENZO(GHI)FLUORANTHENE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-11-20 US disclosed
WO-2008015945-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230140609-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 HPRT1 1948/4885LPL 2338/4885LIPG 2947/4885
US-20090033210-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE TRPA1, LEF1, FLI1 HPRT1 341/4885LPL 672/4885LIPG 807/4885
US-20090079331-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CRY1, OCIAD1, LEF1 HPRT1 69/4885LPL 599/4885LIPG 1274/4885
US-20080286611-A1 BENZO(GHI)FLUORANTHENE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME GTF2I, FLI1, GLB1 HPRT1 238/4885LPL 431/4885LIPG 983/4885
US-20090278447-A1 ORGANIC LUMINESCENT DEVICE AND BENZO[k]FLUORANTHENE COMPOUND FOXK1, KCNK10, F10 HPRT1 1111/4885LPL 550/4885LIPG 1545/4885
US-20100117526-A1 NOVEL AZAINDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE NR2E3, OR51E2, AZI2 HPRT1 152/4885LPL 2012/4885LIPG 2713/4885
US-11903311-B2 Heterocyclic compound and organic light emitting device comprising the same CYP1A1, CYP1B1, CHRM1 HPRT1 1607/4885LPL 3195/4885LIPG 4673/4885
US-20180337348-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, ORC3 HPRT1 17/4885LPL 2509/4885LIPG 3299/4885
US-12167689-B2 Heterocyclic compound and organic light emitting device comprising the same C1S, ARRB1, CRY1 HPRT1 1750/4885LPL 2818/4885LIPG 4464/4885
US-20220336757-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME C1S, CNR1, ARRB1 HPRT1 1726/4885LPL 3061/4885LIPG 4499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.