Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.60 |
| ▸ | P4HB | P07237 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | KDM1A | O60341 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.50 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015157 | 0.86 | TRPA1 (0.63) | TRPA1P4HBTRPV1KDM1ACYP19A1 | |
| SCHEMBL2961146 | 0.82 | TRPA1 (0.75) | TRPA1P4HBTRPV1KDM1ACYP19A1 | |
| SCHEMBL31233064 | 0.81 | KDM1A (0.81) | TRPA1P4HBTRPV1KDM1ACYP19A1 | |
| SCHEMBL7030024 | 0.80 | CYP19A1 (0.80) | CYP19A1CYP3A4MAOBPTPN1 | |
| SCHEMBL22261653 | 0.79 | SLCO2B1 (0.77) | TRPA1P4HBTRPV1KDM1ACYP19A1 | |
| SCHEMBL22380698 | 0.79 | SLCO2B1 (0.77) | TRPA1P4HBTRPV1KDM1ACYP19A1 | |
| SCHEMBL29351306 | 0.79 | TRPA1 (0.89) | TRPA1P4HBTRPV1KDM1ACYP19A1 | |
| SCHEMBL10015141 | 0.79 | CYP19A1 (0.48) | TRPA1P4HBTRPV1KDM1ACYP19A1 | |
| SCHEMBL31504735 | 0.79 | TRPA1 (0.79) | TRPA1P4HBTRPV1KDM1ACYP19A1 | |
| SCHEMBL10926327 | 0.79 | TRPA1 (0.79) | TRPA1P4HBTRPV1KDM1ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207313-B2 | Natural products from Vinca | WILLIAM MARSH RICE UNIVERSITY (US) | 2012-06-26 | — | — | US | disclosed |
| US-8207313-B2 | Natural products from Vinca | WILLIAM MARSH RICE UNIVERSITY (US) | 2012-06-26 | — | — | US | disclosed |