Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16977255 | 0.93 | TSHR (0.63) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL329863 | 0.93 | TSHR (0.63) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL12891098 | 0.90 | TSHR (0.64) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL16804531 | 0.90 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL14000519 | 0.87 | SMN1; SMN2 (0.68) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL10015522 | 0.86 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL11919877 | 0.86 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL19448719 | 0.86 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL26664442 | 0.86 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL329824 | 0.86 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2237672-B1 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE SURFACTANTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-04-27 | — | — | EP | disclosed |
| US-8367740-B2 | Hydrolysis resistant organomodified disiloxane ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367740-B2 | Hydrolysis resistant organomodified disiloxane ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20110201505-A1 | MIXTURES COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-08-18 | — | — | US | disclosed |
| US-20110201505-A1 | MIXTURES COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-08-18 | — | — | US | disclosed |
| CN-101959417-A | Hydrolysis resistant organomodified disiloxane ionic surfactants | MOMENTIVE PERFORMANCE MAT INC (US) | 2011-01-26 | — | — | CN | disclosed |
| CN-101959418-A | The mixture that comprises the organically-modified disiloxane ionic surfactant of anti-hydrolysis | MOMENTIVE PERFORMANCE MAT INC | 2011-01-26 | — | — | CN | disclosed |
| US-20110011308-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-01-20 | — | — | US | disclosed |
| US-20110011308-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-01-20 | — | — | US | disclosed |
| US-20110015075-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-01-20 | — | — | US | disclosed |
| US-20110015075-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-01-20 | — | — | US | disclosed |
| EP-2237672-A2 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE SURFACTANTS | Momentive Performance Materials Inc. (US) | 2010-10-13 | — | — | EP | disclosed |
| EP-2237671-A2 | MIXTURES COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | Momentive Performance Materials Inc. (US) | 2010-10-13 | — | — | EP | disclosed |
| US-20090173913-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | US | disclosed |
| US-20090173913-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | US | disclosed |
| WO-2009085299-A2 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085298-A2 | MIXTURES COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085298-A2 | MIXTURES COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| US-20090171108-A1 | MIXTURES COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-02 | — | — | US | disclosed |
| US-20090171108-A1 | MIXTURES COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090171108-A1 | MIXTURES COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | GHITM, PLOD3, MET | TSHR 586/4885SMN1; SMN2 753/4885ALDH1A1 4263/4885 |
| US-20110015075-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MSMO1, MGAM, MGLL | TSHR 1239/4885SMN1; SMN2 724/4885ALDH1A1 2482/4885 |
| US-20090173913-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MSMO1, MGAM, MGLL | TSHR 1239/4885SMN1; SMN2 724/4885ALDH1A1 2482/4885 |
| US-20110201505-A1 | MIXTURES COMPRISING HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MGAM, MSMO1, MGLL | TSHR 1149/4885SMN1; SMN2 636/4885ALDH1A1 2614/4885 |
| US-20110011308-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED DISILOXANE IONIC SURFACTANTS | MSMO1, MGAM, MGLL | TSHR 1239/4885SMN1; SMN2 724/4885ALDH1A1 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.