Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24654650 | 0.89 | L3MBTL1 (0.78) | PTK2L3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL1431137 | 0.85 | PTK2 (1.00) | PTK2L3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL614739 | 0.84 | L3MBTL1 (0.70) | PTK2L3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL30481206 | 0.83 | PTK2 (0.65) | PTK2L3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL1503835 | 0.83 | PTK2 (0.65) | PTK2L3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL2632202 | 0.82 | L3MBTL1 (0.68) | PTK2L3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL209867 | 0.82 | L3MBTL1 (0.68) | PTK2L3MBTL1TDP1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL329950 | 0.82 | L3MBTL1 (0.68) | PTK2L3MBTL1TDP1RAB9ANPC1 | |
| Lithium SCHEMBL209869 | 0.82 | L3MBTL1 (0.68) | PTK2L3MBTL1TDP1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL30722380 | 0.81 | PTK2 (0.63) | PTK2L3MBTL1TDP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179226-A1 | Processes for the Preparation of Edoxaban and Intermediates Thereof | THE BANK OF NOVA SCOTIA (CA) | 2018-06-28 | — | — | US | disclosed |
| EP-2602242-B1 | PROCESS FOR PREPARING COMPOUND BY NOVEL SANDMEYER-LIKE REACTION USING NITROXIDE RADICAL COMPOUND AS REACTION CATALYST | DAIICHI SANKYO CO LTD (JP) | 2017-08-23 | — | — | EP | disclosed |
| US-9447118-B2 | Preparation method of optically active diamine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-20 | — | — | US | disclosed |
| US-20160016974-A1 | PREPARATION METHOD OF OPTICALLY ACTIVE DIAMINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-01-21 | — | — | US | disclosed |
| US-20150353577-A1 | METHOD FOR PRODUCING (1S,4S,5S)-4-BROMO-6-OXABICYCLO[3.2.1]OCTAN-7-ONE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-12-10 | — | — | US | disclosed |
| US-9175012-B2 | Method for producing optically active diamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-11-03 | — | — | US | disclosed |
| US-8901345-B2 | Process for preparation of optically active diamine derivative salt | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20130165657-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-06-27 | — | — | US | disclosed |
| US-20130165657-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-06-27 | — | — | US | disclosed |
| US-8357808-B2 | Process for producing diamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-22 | — | — | US | disclosed |
| US-20120041206-A1 | PROCESS FOR PRODUCING DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120035369-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353577-A1 | METHOD FOR PRODUCING (1S,4S,5S)-4-BROMO-6-OXABICYCLO[3.2.1]OCTAN-7-ONE | F7, MAOA, F13A1 | PTK2 1377/4885L3MBTL1 3879/4885TDP1 692/4885 |
| US-20120041206-A1 | PROCESS FOR PRODUCING DIAMINE DERIVATIVE | TFPI, TFPI2, DAO | PTK2 3801/4885L3MBTL1 3736/4885TDP1 404/4885 |
| US-20130165657-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | TFPI, F12, TFPI2 | PTK2 3842/4885L3MBTL1 4419/4885TDP1 662/4885 |
| US-20160016974-A1 | PREPARATION METHOD OF OPTICALLY ACTIVE DIAMINE COMPOUND | F12, F8, F11 | PTK2 4223/4885L3MBTL1 4199/4885TDP1 2599/4885 |
| US-20120035369-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE DIAMINE DERIVATIVE | F12, DAO, TFPI | PTK2 3816/4885L3MBTL1 4143/4885TDP1 1541/4885 |
| US-20180179226-A1 | Processes for the Preparation of Edoxaban and Intermediates Thereof | VKORC1, CYP2C9, VKORC1L1 | PTK2 2927/4885L3MBTL1 4822/4885TDP1 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.