SCHEMBL10015740

SCHEMBL10015740

Cc1ccccc1/C=C/c1ccc(N(c2ccc(/C=C/c3ccccc3C)cc2)c2ccc(/C=C/c3ccccc3C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.56
KDM4E B2RXH2 2/20 0.56
APOBEC3A P31941 1/20 0.56
APOBEC3G Q9HC16 1/20 0.56
APP P05067 2/20 0.50
RELA Q04206 3/20 0.47
NFE2L2 Q16236 5/20 0.46
TSHR P16473 2/20 0.44
CYP1A2 P05177 2/20 0.44
TP53 P04637 1/20 0.44
CYP2D6 P10635 1/20 0.44
THPO P40225 1/20 0.44
HIF1A Q16665 1/20 0.44
FGF23 Q9GZV9 1/20 0.42
CHAT P28329 1/20 0.42
MEN1 O00255 1/20 0.42
PABPC1 P11940 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 2/20 0.42
CTDSP1 Q9GZU7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12376973 0.95 NFE2L2 (0.54) RAB9AKDM4EAPOBEC3AAPOBEC3GAPP
SCHEMBL14665754 0.95 NFE2L2 (0.54) RAB9AKDM4EAPOBEC3AAPOBEC3GAPP
SCHEMBL14196503 0.90 RAB9A (0.47) RAB9AKDM4EAPOBEC3AAPOBEC3GAPP
SCHEMBL14727216 0.90 NFE2L2 (0.50) RAB9AKDM4EAPOBEC3AAPOBEC3GAPP
SCHEMBL29403804 0.88 RAB9A (0.68) RAB9AKDM4EAPOBEC3AAPOBEC3GAPP
SCHEMBL318135 0.88 RAB9A (0.68) RAB9AKDM4EAPOBEC3AAPOBEC3GAPP
SCHEMBL142258 0.88 RAB9A (0.68) RAB9AKDM4EAPOBEC3AAPOBEC3GAPP
SCHEMBL14895393 0.87 APP (0.67) RAB9AKDM4EAPOBEC3AAPOBEC3GAPP
SCHEMBL4400856 0.85 NFE2L2 (0.59) RAB9AKDM4EAPOBEC3AAPOBEC3GAPP
SCHEMBL11671982 0.85 NFE2L2 (0.59) RAB9AKDM4EAPOBEC3AAPOBEC3GAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8859818-B2 Electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-10-14 US disclosed
US-8859818-B2 Electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-10-14 US disclosed
US-20120022293-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-01-26 US disclosed
US-20120022293-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022293-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR SLC1A2, SLC18A2, SLC1A1 RAB9A 2074/4885KDM4E 3261/4885APOBEC3A 4228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.