SCHEMBL12376973

SCHEMBL12376973

Cc1ccc(N(c2ccc(C)cc2)c2ccc(/C=C/c3ccccc3C)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 5/20 0.54
RAB9A P51151 3/20 0.51
KDM4E B2RXH2 1/20 0.51
APOBEC3A P31941 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
FGF23 Q9GZV9 1/20 0.50
APP P05067 2/20 0.46
RELA Q04206 2/20 0.43
TSHR P16473 2/20 0.41
ALOX5 P09917 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
THPO P40225 1/20 0.41
HIF1A Q16665 1/20 0.41
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14665754 1.00 NFE2L2 (0.54) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL14727216 0.95 NFE2L2 (0.50) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL10015740 0.95 RAB9A (0.56) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL11671982 0.91 NFE2L2 (0.59) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL4400856 0.91 NFE2L2 (0.59) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL16105485 0.89 NFE2L2 (0.66) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL16105486 0.89 NFE2L2 (0.66) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL16105484 0.89 NFE2L2 (0.66) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL1626237 0.88 NFE2L2 (0.46) NFE2L2RAB9AKDM4EAPOBEC3AAPOBEC3G
SCHEMBL22502948 0.88 NFE2L2 (0.56) NFE2L2RAB9AKDM4EFGF23APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 US disclosed