SCHEMBL10015751

SCHEMBL10015751

C=CC(=O)Oc1ccc(-c2ccc(OC(=O)c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.50
ALDH5A1 P51649 1/20 0.46
ABAT P80404 1/20 0.46
THRB P10828 2/20 0.44
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HSD17B10 Q99714 2/20 0.43
PARP10 Q53GL7 1/20 0.42
HSD17B1 P14061 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
F2 P00734 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
ELANE P08246 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16429576 0.95 ALDH5A1 (0.50) SENP1ALDH5A1ABATTHRBHSD17B10
SCHEMBL10015752 0.95 ALDH5A1 (0.50) SENP1ALDH5A1ABATTHRBHSD17B10
SCHEMBL18608266 0.95 ALDH5A1 (0.50) SENP1ALDH5A1ABATTHRBHSD17B10
SCHEMBL14370491 0.95 ALDH5A1 (0.50) SENP1ALDH5A1ABATTHRBHSD17B10
SCHEMBL22566480 0.93 THRB (0.49) THRBLMNAHSD17B10PARP10F2
SCHEMBL22566606 0.93 THRB (0.49) THRBLMNAHSD17B10PARP10F2
SCHEMBL21470125 0.93 THRB (0.49) THRBLMNAHSD17B10PARP10F2
SCHEMBL15695635 0.93 THRB (0.49) THRBLMNAHSD17B10PARP10F2
SCHEMBL824857 0.90 THRB (0.51) ALDH5A1ABATTHRBKDM4EHSD17B10
SCHEMBL20938271 0.88 SENP1 (0.61) SENP1LMNAKDM4EHSD17B10PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8535769-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and oriented film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-17 US disclosed
US-8123977-B2 Copolymer for liquid crystal alignment, liquid crystal aligning layer including copolymer for liquid crystal alignment, and liquid crystal display including liquid crystal aligning layer LG CHEM, LTD. (KR) 2012-02-28 US disclosed
US-8123977-B2 Copolymer for liquid crystal alignment, liquid crystal aligning layer including copolymer for liquid crystal alignment, and liquid crystal display including liquid crystal aligning layer LG CHEM, LTD. (KR) 2012-02-28 US disclosed
US-20070102668-A1 Copolymer for liquid crystal alignment , liquid crystal aligning layer including copolymer for liquid crystal alignment, and liquid crystal display including liquid crystal aligning layer LG CHEM, LTD. (KR) 2007-05-10 US disclosed
US-20070102668-A1 Copolymer for liquid crystal alignment , liquid crystal aligning layer including copolymer for liquid crystal alignment, and liquid crystal display including liquid crystal aligning layer LG CHEM, LTD. (KR) 2007-05-10 US disclosed