Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | DCK | P27707 | 17/20 | 0.40 |
| ▸ | POLG | P54098 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119054 | 0.81 | ALB (0.61) | ALBDCKPOLG | |
| SCHEMBL9066867 | 0.81 | ALB (0.61) | ALBDCKPOLG | |
| SCHEMBL20734859 | 0.81 | ALB (0.61) | ALBDCKPOLG | |
| SCHEMBL5607740 | 0.81 | ALB (0.61) | ALBDCKPOLG | |
| SCHEMBL9066905 | 0.81 | ALB (0.61) | ALBDCKPOLG | |
| SCHEMBL5608119 | 0.81 | ALB (0.61) | ALBDCKPOLG | |
| SCHEMBL13881252 | 0.76 | LMNA (0.44) | ALBPOLG | |
| SCHEMBL10015810 | 0.76 | LMNA (0.44) | ALBPOLG | |
| SCHEMBL3965514 | 0.76 | ALB (0.51) | ALBDCKPOLG | |
| SCHEMBL20735176 | 0.75 | ALB (0.54) | ALBDCKPOLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110676-B2 | Prodrugs activated by RNA-dependent DNA-polymerases | PROTERA S.R.L. (IT) | 2012-02-07 | — | — | US | disclosed |
| US-20080300215-A1 | Prodrugs Activated by Rna-Dependent Dna-Polymerases | PROTERA S.R.L. (IT) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300215-A1 | Prodrugs Activated by Rna-Dependent Dna-Polymerases | TERT, POLRMT, POLI | ALB 4511/4885DCK 150/4885POLG 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.