Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2758531 | 1.00 | HTT (0.63) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL2758532 | 0.94 | PTGS2 (0.58) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL19105488 | 0.94 | HTT (0.73) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL20149706 | 0.94 | PTGS2 (0.58) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL12708896 | 0.94 | PTGS2 (0.58) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL23153426 | 0.94 | HTT (0.73) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL10016733 | 0.94 | HTT (0.73) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL11547843 | 0.91 | HTT (0.58) | HTTSMN1; SMN2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL19341781 | 0.89 | HTT (0.53) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 | |
| SCHEMBL9888806 | 0.89 | HTT (0.67) | HTTSMN1; SMN2TDP1L3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550216-B2 | Composite solid polymer electrolyte membranes | FOSTER-MILLER, INC. (US) | 2009-06-23 | — | — | US | disclosed |