SCHEMBL2758531

SCHEMBL2758531

Cc1ccc(Oc2ccc(S(C)(=O)=O)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 5/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
PTGS2 P35354 7/20 0.55
PTGS1 P23219 3/20 0.54
FFAR1 O14842 1/20 0.53
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
TEAD4 Q15561 1/20 0.50
GAA P10253 1/20 0.50
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
GFER P55789 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13814624 1.00 HTT (0.63) HTTSMN1; SMN2TDP1L3MBTL1PTGS2
SCHEMBL2758532 0.94 PTGS2 (0.58) HTTSMN1; SMN2TDP1L3MBTL1PTGS2
SCHEMBL19105488 0.94 HTT (0.73) HTTSMN1; SMN2TDP1L3MBTL1PTGS2
SCHEMBL20149706 0.94 PTGS2 (0.58) HTTSMN1; SMN2TDP1L3MBTL1PTGS2
SCHEMBL12708896 0.94 PTGS2 (0.58) HTTSMN1; SMN2TDP1L3MBTL1PTGS2
SCHEMBL23153426 0.94 HTT (0.73) HTTSMN1; SMN2TDP1L3MBTL1PTGS2
SCHEMBL10016733 0.94 HTT (0.73) HTTSMN1; SMN2TDP1L3MBTL1PTGS2
SCHEMBL11547843 0.91 HTT (0.58) HTTSMN1; SMN2PTGS2PTGS1ALDH1A1
SCHEMBL19341781 0.89 HTT (0.53) HTTSMN1; SMN2TDP1L3MBTL1PTGS2
SCHEMBL9888806 0.89 HTT (0.67) HTTSMN1; SMN2TDP1L3MBTL1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226816-A1 CO2 GAS ENRICHMENT METHOD KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-07-11 US disclosed
US-20240207543-A1 COATING PROCESS JPMORGAN CHASE BANK, N.A. 2024-06-27 US disclosed
US-20240207543-A1 COATING PROCESS JPMORGAN CHASE BANK, N.A. 2024-06-27 US disclosed
US-11779716-B2 Method for making medicinal delivery device having multi-layer coating KINDEVA DRUG DELIVERY L.P. (US) 2023-10-10 US disclosed
US-20230173434-A1 METHOD FOR SEPARATING A GAS MIXTURE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-06-08 US disclosed
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 US disclosed
US-20230149860-A1 GAS FILTER FOR SEPARATING GASEOUS COMPOSITIONS KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-05-18 US disclosed
EP-2843743-B1 Membrane electrode units for high temperature fuel cells with improved stability BASF SE (DE) 2018-03-28 EP disclosed
EP-2871180-B1 2-AMINONICOTINIC ACID ESTER DERIVATIVE AND BACTERICIDE CONTAINING SAME AS ACTIVE INGREDIENT AGRO KANESHO CO LTD (JP) 2018-03-21 EP disclosed
US-20170266652-A1 FUNCTIONALIZED MAIN CHAIN POLYMERS HÄRING THOMAS (DE) 2017-09-21 US disclosed
US-20080027061-A1 omega-Carboxy Aryl Substituted Diphenyl Ureas As p38 Kinase Inhibitors BAYER HEALTHCARE LLC 2008-01-31 US disclosed
EP-1636585-B1 DIARYL UREAS WITH KINASE INHIBITING ACTIVITY BAYER PHARMACEUTICALS CORP (US) 2008-01-16 EP disclosed
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BAYER HEALTHCARE LLC 2007-10-18 US disclosed
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BAYER HEALTHCARE LLC 2007-10-18 US disclosed
US-7235576-B1 Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors BAYER PHARMACEUTICALS CORPORATION (US) 2007-06-26 US disclosed
US-7235576-B1 Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors BAYER PHARMACEUTICALS CORPORATION (US) 2007-06-26 US disclosed
WO-2007053574-A2 COMBINATIONS COMPRISING SORAFENIB AND INTERFERON FOR THE TREATMENT OF CANCER BAYER PHARMACEUTICALS CORPORATION (US) 2007-05-10 WO disclosed
US-20070020704-A1 Diaryl ureas with kinase inhibiting activity BAYER HEALTHCARE LLC 2007-01-25 US disclosed
US-20070020704-A1 Diaryl ureas with kinase inhibiting activity BAYER HEALTHCARE LLC 2007-01-25 US disclosed
US-6294573-B1 FOR THERAPY RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPENIAS SUCH AS OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL, EPIDERMAL OR GASTRIC ULCERATION, AND TUMOR GROWTH AND METASTASIS OR INVASION ABBOTT LABORATORIES 2001-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF SSB, EBNA1BP2, PML HTT 3116/4885SMN1; SMN2 2894/4885TDP1 2118/4885
US-20070020704-A1 Diaryl ureas with kinase inhibiting activity FLT4, FLT1, FLT3 HTT 1957/4885SMN1; SMN2 4039/4885TDP1 946/4885
US-20080027061-A1 omega-Carboxy Aryl Substituted Diphenyl Ureas As p38 Kinase Inhibitors MAPK1, MAPK8, MAPK3 HTT 3241/4885SMN1; SMN2 2811/4885TDP1 2039/4885
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BRAF, RAF1, ARAF HTT 3520/4885SMN1; SMN2 4560/4885TDP1 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.