⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12753015 | 1.00 | — | — | |
| SCHEMBL13248137 | 1.00 | — | — | |
| SCHEMBL24621340 | 1.00 | — | — | |
| SCHEMBL10016807 | 0.74 | — | — | |
| SCHEMBL10016808 | 0.74 | THRB (0.44) | — | |
| SCHEMBL10048336 | 0.74 | THRB (0.44) | — | |
| SCHEMBL1735065 | 0.74 | THRB (0.44) | — | |
| SCHEMBL15218988 | 0.74 | THRB (0.44) | — | |
| SCHEMBL12753013 | 0.74 | — | — | |
| SCHEMBL196060 | 0.74 | THRB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279486-A1 | 2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF | Guangzhou Salustier Biosciences Co., Ltd. (CN) | 2023-11-22 | — | — | EP | disclosed |
| US-20230348487-A1 | 2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF | GUANGZHOU SALUSTIER BIOSCIENCES CO., LTD. (CN) | 2023-11-02 | — | — | US | disclosed |
| US-8841096-B2 | Method for producing multicyclical ring systems carrying amino groups | EVONIK DEGUSSA GMBH (DE) | 2014-09-23 | — | — | US | disclosed |
| US-20120041216-A1 | METHOD FOR PRODUCING MULTICYCLICAL RING SYSTEMS CARRYING AMINO GROUPS | EVONIK DEGUSSA GMBH (DE) | 2012-02-16 | — | — | US | disclosed |