Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196060 | 1.00 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL10016808 | 1.00 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL1735065 | 1.00 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL15218988 | 1.00 | THRB (0.44) | THRBLMNAMAPT | |
| Isosorbide SCHEMBL699485 | 0.96 | THRB (0.52) | THRBLMNAMAPT | |
| SCHEMBL10552467 | 0.75 | THRB (0.41) | THRBLMNAMAPT | |
| SCHEMBL24621340 | 0.74 | — | — | |
| SCHEMBL372212 | 0.74 | THRB (0.44) | THRBLMNA | |
| SCHEMBL8293189 | 0.74 | THRB (0.44) | THRBLMNA | |
| SCHEMBL10016807 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | disclosed |
| WO-2018112774-A1 | PROCESS FOR PREPARING ISOMANNIDE, MONOKETONES AND MIXTURES THEREOF | RHODIA OPERATIONS (FR) | 2018-06-28 | — | — | WO | disclosed |
| WO-2016099788-A1 | PREPARATION OF ISOHEXIDE TRIFLUOROACETATES | ARCHER DANIELS MIDLAND COMPANY (US) | 2016-06-23 | — | — | WO | disclosed |
| US-20120041216-A1 | METHOD FOR PRODUCING MULTICYCLICAL RING SYSTEMS CARRYING AMINO GROUPS | EVONIK DEGUSSA GMBH (DE) | 2012-02-16 | — | — | US | disclosed |
| US-20110077254-A1 | COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2011-03-31 | — | — | US | disclosed |
| US-20070254920-A1 | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use | AERIE PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | US | disclosed |
| EP-0230557-A2 | 2,6-Dioxabicyclo[3.3.0]octane derivatives, their preparation and use as medicament | Heinrich Mack Nachf. (DE) | 1987-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254920-A1 | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use | HCAR1, HCAR2, PAICS | THRB 1067/4885LMNA 3188/4885MAPT 3694/4885 |
| US-20110077254-A1 | COMPOUNDS | CHRM1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PRMT9 | THRB 1107/4885LMNA 1409/4885MAPT 1751/4885 |
| US-20120041216-A1 | METHOD FOR PRODUCING MULTICYCLICAL RING SYSTEMS CARRYING AMINO GROUPS | AKR7A2, AADAT, OAT | THRB 3156/4885LMNA 2418/4885MAPT 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.