Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196060 | 1.00 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL1735065 | 1.00 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL15218988 | 1.00 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL10048336 | 1.00 | THRB (0.44) | THRBLMNAMAPT | |
| Isosorbide SCHEMBL699485 | 0.96 | THRB (0.52) | THRBLMNAMAPT | |
| SCHEMBL10552467 | 0.75 | THRB (0.41) | THRBLMNAMAPT | |
| SCHEMBL24621340 | 0.74 | — | — | |
| SCHEMBL372212 | 0.74 | THRB (0.44) | THRBLMNA | |
| SCHEMBL8293189 | 0.74 | THRB (0.44) | THRBLMNA | |
| SCHEMBL10016807 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018112774-A1 | PROCESS FOR PREPARING ISOMANNIDE, MONOKETONES AND MIXTURES THEREOF | RHODIA OPERATIONS (FR) | 2018-06-28 | — | — | WO | disclosed |
| EP-2817314-B1 | METHOD OF MAKING ISOIDIDE | STICHTING WAGENINGEN RES (NL) | 2017-04-19 | — | — | EP | disclosed |
| EP-3056496-A1 | METHOD OF MAKING ISOIDIDE | Stichting Dienst Landbouwkundig Onderzoek (NL) | 2016-08-17 | — | — | EP | disclosed |
| US-9340552-B2 | Method of making isoidide | ARCHER DANIELS MIDLAND COMPANY (US) | 2016-05-17 | — | — | US | disclosed |
| US-20140371472-A1 | METHOD OF MAKING ISOIDIDE | STICHTING DIENST LANDBOUWKUNDI (NL) | 2014-12-18 | — | — | US | disclosed |
| US-8841096-B2 | Method for producing multicyclical ring systems carrying amino groups | EVONIK DEGUSSA GMBH (DE) | 2014-09-23 | — | — | US | disclosed |
| US-8841096-B2 | Method for producing multicyclical ring systems carrying amino groups | EVONIK DEGUSSA GMBH (DE) | 2014-09-23 | — | — | US | disclosed |
| WO-2013125950-A1 | METHOD OF MAKING ISOIDIDE | STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) | 2013-08-29 | — | — | WO | disclosed |
| US-8378127-B2 | Method for producing 2,6-dioxabicyclo-(3.3.0)-octane-4,8-dione | EVONIK DEGUSSA GMBH (DE) | 2013-02-19 | — | — | US | disclosed |
| US-20120041216-A1 | METHOD FOR PRODUCING MULTICYCLICAL RING SYSTEMS CARRYING AMINO GROUPS | EVONIK DEGUSSA GMBH (DE) | 2012-02-16 | — | — | US | disclosed |
| US-20120041216-A1 | METHOD FOR PRODUCING MULTICYCLICAL RING SYSTEMS CARRYING AMINO GROUPS | EVONIK DEGUSSA GMBH (DE) | 2012-02-16 | — | — | US | disclosed |
| EP-0230557-A2 | 2,6-Dioxabicyclo[3.3.0]octane derivatives, their preparation and use as medicament | Heinrich Mack Nachf. (DE) | 1987-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371472-A1 | METHOD OF MAKING ISOIDIDE | SI, HSD11B2, HSD11B1 | THRB 4597/4885LMNA 4552/4885MAPT 3624/4885 |
| US-20120041216-A1 | METHOD FOR PRODUCING MULTICYCLICAL RING SYSTEMS CARRYING AMINO GROUPS | AKR7A2, AADAT, OAT | THRB 3156/4885LMNA 2418/4885MAPT 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.