SCHEMBL10017530

SCHEMBL10017530

C=CC(=O)OCCOc1ccc(N)cc1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.51
ALDH1A1 P00352 4/20 0.50
TP53 P04637 3/20 0.50
USP2 O75604 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
CASP1 P29466 1/20 0.50
HTT P42858 1/20 0.50
CASP7 P55210 1/20 0.50
KMT2A Q03164 1/20 0.50
ATM Q13315 1/20 0.50
TSHR P16473 5/20 0.43
HIF1A Q16665 2/20 0.43
HSD17B10 Q99714 2/20 0.43
PRSS1 P07477 8/20 0.42
CYP3A4 P08684 2/20 0.40
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11999078 0.92 ALDH1A1 (0.53) THRBALDH1A1TP53USP2KDM4E
SCHEMBL11994867 0.87 ALDH1A1 (0.44) THRBALDH1A1TP53USP2KDM4E
SCHEMBL19980860 0.86 THRB (0.54) THRBALDH1A1TP53USP2KDM4E
SCHEMBL3633964 0.81 THRB (0.45) THRBALDH1A1TP53TSHRHIF1A
SCHEMBL10717019 0.79 THRB (0.44) THRBALDH1A1TP53KDM4EMEN1
SCHEMBL29217763 0.79 ALDH1A1 (0.47) THRBALDH1A1USP2KDM4EMEN1
SCHEMBL3691364 0.79 THRB (0.46) THRBALDH1A1TP53USP2MEN1
SCHEMBL8099817 0.79 GAA (0.74) THRBALDH1A1TP53USP2KDM4E
SCHEMBL19624186 0.78 THRB (0.71) THRBALDH1A1TP53KDM4EMEN1
SCHEMBL10017529 0.78 POLB (0.53) THRBALDH1A1TP53USP2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170038643-A1 DISPLAY PANEL AND MANUFACTURING METHOD THEREOF AU OPTRONICS CORPORATION (TW) 2017-02-09 US disclosed
US-20170038643-A1 DISPLAY PANEL AND MANUFACTURING METHOD THEREOF AU OPTRONICS CORPORATION (TW) 2017-02-09 US disclosed
US-20120026440-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME SONY CORPORATION (JP) 2012-02-02 US disclosed