Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691364 | 0.89 | THRB (0.46) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL20207218 | 0.86 | TSHR (0.42) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10718237 | 0.84 | THRB (0.37) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL28626780 | 0.82 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL8038786 | 0.81 | THRB (0.55) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10717019 | 0.81 | THRB (0.44) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10017530 | 0.81 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL16389889 | 0.80 | TKT (0.41) | TSHRALDH1A1TP53CYP3A4NPC1 | |
| SCHEMBL15600713 | 0.78 | AKR1B10 (0.60) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10823792 | 0.78 | NPC1 (0.51) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142957-A1 | METHOD OF UNIFORM AND DEFECT FREE LIQUID CRYSTAL ALIGNING LAYERS | Rolic AG (CH) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008119449-A1 | METHOD OF UNIFORM AND DEFECT FREE LIQUID CRYSTAL ALIGNING LAYERS | ROLIC AG (CH) | 2008-10-09 | — | — | WO | disclosed |