SCHEMBL10018009

SCHEMBL10018009

CC(C)=CCCCC(C)C1CCC2C3CC=C4C(C)(C)CC(OC(=O)c5cc(N)cc(N)c5)CC4(C)C3CCC12C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 5/20 0.51
OSBP P22059 6/20 0.45
OSBP2 Q969R2 3/20 0.45
GRIN1 Q05586 3/20 0.45
GRIN2A Q12879 3/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
ABCB1 P08183 1/20 0.45
CYP46A1 Q9Y6A2 1/20 0.45
NR1H3 Q13133 7/20 0.44
EPHA2 P29317 1/20 0.43
POLA1 P09884 1/20 0.43
PTPN1 P18031 3/20 0.43
CRYAB P02511 1/20 0.43
HMGCR P04035 1/20 0.43
ITGB3 P05106 1/20 0.43
ITGAV P06756 1/20 0.43
SREBF2 Q12772 1/20 0.43
NPC1L1 Q9UHC9 1/20 0.43
GRIN2B Q13224 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12172528 0.87 RORC (0.50) RORCOSBPOSBP2GRIN1GRIN2A
SCHEMBL16265112 0.84 RORC (0.58) RORCOSBPOSBP2GRIN1GRIN2A
SCHEMBL14431387 0.83 RORC (0.48) RORCOSBPOSBP2GRIN1GRIN2A
SCHEMBL10018010 0.83 RORC (0.41) RORCUSP2POLA1NPC1L1
SCHEMBL19853034 0.83 RORC (0.55) RORCOSBPOSBP2GRIN1GRIN2A
SCHEMBL9999687 0.83 RORC (0.55) RORCOSBPOSBP2GRIN1GRIN2A
SCHEMBL2608105 0.83 RORC (0.66) RORCOSBPOSBP2GRIN1GRIN2A
SCHEMBL14902982 0.82 RORC (0.51) RORCOSBPOSBP2GRIN1GRIN2A
SCHEMBL10018006 0.79 POLA1 (0.59) RORCOSBPOSBP2GRIN1GRIN2A
SCHEMBL13383870 0.79 POLA1 (0.59) RORCOSBPOSBP2GRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130083278-A1 LIQUID CRYSTAL DISPLAY DEVICE SHARP KABUSHIKI KAISHA (JP) 2013-04-04 US disclosed
US-8310636-B2 Liquid crystal display device and polymer for aligning film material SHARP KABUSHIKI KAISHA (JP) 2012-11-13 US disclosed
US-20120013836-A1 LIQUID CRYSTAL DISPLAY APPARATUS AND MANUFACTURING METHOD THEREOF SHARP KABUSHIKI KAISHA (JP) 2012-01-19 US disclosed
US-20100085523-A1 LIQUID CRYSTAL DISPLAY DEVICE AND POLYMER FOR ALIGNING FILM MATERIAL SHARP KABUSHIKI KAISHA (JP) 2010-04-08 US disclosed