SCHEMBL10018010

SCHEMBL10018010

CC(C)=CCCCC(C)C1CCC2C3CCC4C(C)(C)CC(OC(=O)c5cc(N)cc(N)c5)CC4(C)C3CCC12C

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.41
VDR P11473 2/20 0.40
USP2 O75604 1/20 0.40
CD4 P01730 3/20 0.39
CCR1 P32246 1/20 0.39
CDC25A P30304 3/20 0.39
POLA1 P09884 1/20 0.39
NPC1L1 Q9UHC9 1/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
ST6GAL1 P15907 2/20 0.38
CYP2C9 P11712 1/20 0.37
HIF1A Q16665 1/20 0.37
GPBAR1 Q8TDU6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12172527 0.87 RORC (0.41) RORCVDRUSP2CD4CCR1
SCHEMBL16265131 0.85 VDR (0.47) RORCVDRUSP2ST6GAL1CYP2C9
SCHEMBL10018009 0.83 RORC (0.51) RORCUSP2POLA1NPC1L1
SCHEMBL15935558 0.82 RORC (0.46) RORCVDRUSP2CYP2C9HIF1A
SCHEMBL2608103 0.82 VDR (0.57) VDRUSP2CDC25APOLA1ST6GAL1
SCHEMBL10015978 0.82 RORC (0.46) RORCVDRUSP2CYP2C9HIF1A
SCHEMBL14902980 0.81 RORC (0.41) RORCUSP2CD4CCR1NPC1L1
SCHEMBL10018007 0.80 CDC25A (0.56) VDRUSP2CDC25APOLA1FNTA
SCHEMBL13383871 0.80 CDC25A (0.56) VDRUSP2CDC25APOLA1FNTA
SCHEMBL12172528 0.79 RORC (0.50) RORCUSP2POLA1NPC1L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130083278-A1 LIQUID CRYSTAL DISPLAY DEVICE SHARP KABUSHIKI KAISHA (JP) 2013-04-04 US disclosed
US-8310636-B2 Liquid crystal display device and polymer for aligning film material SHARP KABUSHIKI KAISHA (JP) 2012-11-13 US disclosed
US-20120013836-A1 LIQUID CRYSTAL DISPLAY APPARATUS AND MANUFACTURING METHOD THEREOF SHARP KABUSHIKI KAISHA (JP) 2012-01-19 US disclosed
US-20100085523-A1 LIQUID CRYSTAL DISPLAY DEVICE AND POLYMER FOR ALIGNING FILM MATERIAL SHARP KABUSHIKI KAISHA (JP) 2010-04-08 US disclosed