SCHEMBL14431387

SCHEMBL14431387

CC(C)=CCCCC(C)C1CCC2C3CC=C4C(C)(C)C(OC(=O)c5cc(N)cc([SiH3])c5)CCC4(C)C3CCC12C

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RORC P51449 4/20 0.48
PTPN1 P18031 4/20 0.43
OSBP P22059 4/20 0.42
OSBP2 Q969R2 2/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
ABCB1 P08183 1/20 0.42
CYP46A1 Q9Y6A2 1/20 0.42
NR1H3 Q13133 5/20 0.41
EPHA2 P29317 1/20 0.41
POLA1 P09884 1/20 0.41
CRYAB P02511 1/20 0.40
HMGCR P04035 1/20 0.40
ITGB3 P05106 1/20 0.40
ITGAV P06756 1/20 0.40
SREBF2 Q12772 1/20 0.40
NPC1L1 Q9UHC9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12172528 0.96 RORC (0.50) RORCPTPN1OSBPOSBP2GRIN1
SCHEMBL9999687 0.92 RORC (0.55) RORCPTPN1OSBPOSBP2GRIN1
SCHEMBL19853034 0.92 RORC (0.55) RORCPTPN1OSBPOSBP2GRIN1
SCHEMBL9999571 0.86 OSBP (0.53) RORCPTPN1OSBPOSBP2GRIN1
SCHEMBL10018009 0.83 RORC (0.51) RORCPTPN1OSBPOSBP2GRIN1
SCHEMBL10017594 0.82 RORC (0.50) RORCPTPN1OSBPOSBP2GRIN1
SCHEMBL11999082 0.81 RORC (0.49) RORCPTPN1OSBPOSBP2GRIN1
SCHEMBL12172527 0.80 RORC (0.41) RORCPTPN1USP2LMNAEPHA2
SCHEMBL16015441 0.80 RORC (0.43) RORCPTPN1OSBPOSBP2GRIN1
SCHEMBL106036 0.80 RORC (0.58) RORCPTPN1OSBPOSBP2GRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070190267-A1 Composition for forming liquid crystal orientation film, apparatus for forming liquid orientation film, and liquid crystal display SEIKO EPSON CORPORATION 2007-08-16 US disclosed