SCHEMBL8986779

SCHEMBL8986779

CCC(C)(C)C(=O)NCCCN

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 3/20 0.44
RIPK1 Q13546 3/20 0.43
DRD2 P14416 2/20 0.41
DRD4 P21917 2/20 0.41
EPHX1 P07099 2/20 0.40
POLB P06746 2/20 0.39
ALDH1A1 P00352 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
DPP7 Q9UHL4 1/20 0.36
CNR1 P21554 1/20 0.36
RRM1 P23921 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16256508 0.94 PAOX (0.52) PAOXRIPK1DRD2DRD4EPHX1
SCHEMBL10297996 0.88 RIPK1 (0.46) PAOXRIPK1DRD2DRD4EPHX1
SCHEMBL13450761 0.87 EPHX1 (0.50) RIPK1DRD2DRD4EPHX1POLB
SCHEMBL25492568 0.86 CHRNA1 (0.38) PAOXRIPK1DRD2DRD4EPHX1
SCHEMBL4546721 0.85 EPHX1 (0.53) RIPK1DRD2DRD4EPHX1POLB
SCHEMBL14134865 0.85 EPHX1 (0.53) RIPK1DRD2DRD4EPHX1POLB
SCHEMBL10018015 0.84 PAOX (0.44) PAOXEPHX1POLBALDH1A1SMN1; SMN2
SCHEMBL5021617 0.83 EPHX1 (0.52) RIPK1DRD2DRD4EPHX1POLB
SCHEMBL14153992 0.83 RIPK1 (0.52) RIPK1DRD2DRD4EPHX1POLB
SCHEMBL24146674 0.82 PAOX (0.42) PAOXEPHX1POLBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230338415-A1 SUBSTITUTED PHENYL BORONIC ACID CONTAINING POLYMERS AND METHODS OF USE GLYSCEND, INC. 2023-10-26 US disclosed
US-20230338415-A1 SUBSTITUTED PHENYL BORONIC ACID CONTAINING POLYMERS AND METHODS OF USE GLYSCEND, INC. 2023-10-26 US disclosed
US-20230295457-A1 SURFACE TREATMENT LIQUID AND SURFACE TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2023-09-21 US disclosed
EP-3553147-B1 SURFACE TREATMENT LIQUID AND SURFACE TREATMENT METHOD TOKYO OHKA KOGYO CO LTD (JP) 2022-05-11 EP disclosed
US-9044413-B2 Block polymers, compositions and methods for use for foams, laundry detergents, and shower rinses and coagulants SOLVAY USA INC. (US) 2015-06-02 US disclosed
US-8907033-B2 Polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants SOLVAY USA INC. (US) 2014-12-09 US disclosed
US-20140034076-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2014-02-06 US disclosed
US-8580905-B2 Polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants RHODIA INC. (US) 2013-11-12 US disclosed
US-20130295032-A1 BLOCK POLYMERS, COMPOSITIONS AND METHODS FOR USE FOR FOAMS, LAUNDRY DETERGENTS, AND SHOWER RINSES AND COAGULANTS RHODIA (US) 2013-11-07 US disclosed
US-20130237471-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2013-09-12 US disclosed
US-20120208701-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2012-08-16 US disclosed
US-8188204-B2 Polymers, compositions and methods for use for foams, laundry detergents, shower rinses and coagulants RHODIA INC. (US) 2012-05-29 US disclosed
US-20110257015-A1 POLYMERS, COMPOSITIONS AND METHODS FOR USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2011-10-20 US disclosed
US-8017638-B2 Isoxazole derivative and isothiazole derivative having inhibitory activity on 11β-hydroxysteroid dehydrogenase type 1 SHIONOGI & CO., LTD. (JP) 2011-09-13 US disclosed
US-20110183852-A1 BLOCK POLYMERS, COMPOSITIONS AND METHODS FOR USE FOR FOAMS, LAUNDRY DETERGENTS, AND SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2011-07-28 US disclosed
US-7939601-B1 Polymers, compositions and methods of use for foams, laundry detergents, shower rinses, and coagulants RHODIA INC. (US) 2011-05-10 US disclosed
US-7915212-B2 Zwitterionic suds stabilizer; cosmetics; extenders for soaps and shampoos; antideposit agents, and antisoilants; terpolymers such as of hydroxyethyl acrylate-dimethylamino/ethyl methacrylate-acrylic acid; depilatories, cleaning compounds, oil well treatment, shaving gels, coagulants RHODIA INC. (US) 2011-03-29 US disclosed
US-20090131491-A1 ISOXAZOLE DERIVATIVE AND ISOTHIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON 11(beta)-HYDROXYSTEROID DEHYDROGENASE TYPE I SHIONOGI & CO., LTD. (JP) 2009-05-21 US disclosed
US-20080131393-A1 BLOCK POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2008-06-05 US disclosed
US-7335700-B2 Block polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants RHODIA INC. (US) 2008-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208701-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS DSG1, DSTN, TES PAOX 691/4885RIPK1 2799/4885DRD2 1020/4885
US-20130295032-A1 BLOCK POLYMERS, COMPOSITIONS AND METHODS FOR USE FOR FOAMS, LAUNDRY DETERGENTS, AND SHOWER RINSES AND COAGULANTS CUTA, DAGLB, GZMB PAOX 610/4885RIPK1 2477/4885DRD2 1664/4885
US-20110183852-A1 BLOCK POLYMERS, COMPOSITIONS AND METHODS FOR USE FOR FOAMS, LAUNDRY DETERGENTS, AND SHOWER RINSES AND COAGULANTS CUTA, DAGLB, GZMB PAOX 610/4885RIPK1 2477/4885DRD2 1664/4885
US-20230338415-A1 SUBSTITUTED PHENYL BORONIC ACID CONTAINING POLYMERS AND METHODS OF USE SLC10A2, PYGL, SLC10A1 PAOX 293/4885RIPK1 3307/4885DRD2 4073/4885
US-20090131491-A1 ISOXAZOLE DERIVATIVE AND ISOTHIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON 11(beta)-HYDROXYSTEROID DEHYDROGENASE TYPE I HSD3B1, NR5A1, HSD11B1 PAOX 890/4885RIPK1 3417/4885DRD2 591/4885
US-20080131393-A1 BLOCK POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS CUTA, GZMB, DAGLB PAOX 797/4885RIPK1 2377/4885DRD2 1447/4885
US-20110257015-A1 POLYMERS, COMPOSITIONS AND METHODS FOR USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS DSG1, DSTN, TES PAOX 700/4885RIPK1 2792/4885DRD2 1040/4885
US-20140034076-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS DSG1, DSTN, CUTA PAOX 690/4885RIPK1 2817/4885DRD2 964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.