Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654266 | 0.91 | LMNA (0.41) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| Hydrochloric Acid SCHEMBL28261319 | 0.83 | LMNA (0.38) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL7877671 | 0.78 | TRIM24 (0.35) | ESR2TRIM24TRIM33ALDH1A1 | |
| SCHEMBL4620125 | 0.76 | TSHR (0.63) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL5212 | 0.76 | — | — | |
| SCHEMBL21826881 | 0.74 | APLNR (0.37) | ESR2TRIM24TRIM33ALDH1A1 | |
| SCHEMBL16052074 | 0.74 | TRIM24 (0.32) | ESR2TRIM24TRIM33ALDH1A1 | |
| SCHEMBL1202897 | 0.74 | TRIM24 (0.32) | ESR2TRIM24TRIM33ALDH1A1 | |
| Hydrochloric Acid SCHEMBL443213 | 0.74 | — | — | |
| SCHEMBL17159759 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101700-B2 | Phosphonic polymers having a phosphinate backbone and methods of making and using thereof | UNICHEM TECHNOLOGIES, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-8076432-B2 | Phosphonic compounds and methods of use thereof | UNICHEM TECHNOLOGIES, INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-8076432-B2 | Phosphonic compounds and methods of use thereof | UNICHEM TECHNOLOGIES, INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-20100168361-A1 | PHOSPHONIC POLYMERS HAVING A PHOSPHINATE BACKBONE AND METHODS OF MAKING AND USING THEREOF | UNICHEM TECHNOLOGIES, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20090005527-A1 | PHOSPHONIC COMPOUNDS AND METHODS OF USE THEREOF | SUNTRUST BANK | 2009-01-01 | — | — | US | disclosed |
| US-20090005527-A1 | PHOSPHONIC COMPOUNDS AND METHODS OF USE THEREOF | SUNTRUST BANK | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005527-A1 | PHOSPHONIC COMPOUNDS AND METHODS OF USE THEREOF | PHOSPHO1, PPIP5K2, FASN | LMNA 1294/4885CYP3A4 3558/4885GABRA1 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.