Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17057183 | 0.87 | ALOX5 (0.42) | ALOX5MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL21532712 | 0.81 | ALOX5 (0.54) | ALOX5MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL17211241 | 0.80 | MAPT (0.37) | ALOX5MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL27950640 | 0.80 | MAPT (0.49) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL19491746 | 0.80 | MAPT (0.36) | ALOX5MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL30395577 | 0.78 | ALDH1A1 (0.63) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3414807 | 0.78 | ALDH1A1 (0.63) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL15613814 | 0.78 | ALOX5 (0.62) | ALOX5MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL20248372 | 0.78 | ALOX5 (0.48) | ALOX5MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL19543755 | 0.77 | ALOX5 (0.39) | ALOX5MAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8743031-B2 | Dibenzothiophene compound and organic light-emitting element based on the same | CANON KABUSHIKI KAISHA (JP) | 2014-06-03 | — | — | US | disclosed |
| US-8743031-B2 | Dibenzothiophene compound and organic light-emitting element based on the same | CANON KABUSHIKI KAISHA (JP) | 2014-06-03 | — | — | US | disclosed |
| US-20120075171-A1 | DIBENZOTHIOPHENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT BASED ON THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-03-29 | — | — | US | disclosed |
| US-20120075171-A1 | DIBENZOTHIOPHENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT BASED ON THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120075171-A1 | DIBENZOTHIOPHENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT BASED ON THE SAME | TPT1, RFT1, ARNT | ALOX5 2608/4885MAPT 1249/4885NPC1 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.