SCHEMBL10019367

SCHEMBL10019367

CCCCCc1ccc(OC(=O)c2ccc3c(c2F)C(F)C(F)c2c-3ccc(CCC)c2F)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.43
THRA P10827 2/20 0.41
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
RARB P10826 3/20 0.38
RARA P10276 1/20 0.38
RARG P13631 1/20 0.38
FAAH O00519 1/20 0.36
PLA2G1B P04054 1/20 0.36
KMT2A Q03164 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
PPARA Q07869 3/20 0.35
ALDH1A1 P00352 1/20 0.34
PPARG P37231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019637 0.89 PRSS1 (0.39) MAPTSMN1; SMN2NPC1CASP3RAB9A
SCHEMBL10019691 0.87 PPARA (0.39) RARBRARARARGFAAHPPARA
SCHEMBL10019371 0.87 THRB (0.40) THRBMAPTSMN1; SMN2NPC1CASP3
SCHEMBL10019369 0.87 CTSL (0.34) THRBTHRARARBRARARARG
SCHEMBL10020071 0.84 PPARA (0.34) THRBTHRARARBRARARARG
SCHEMBL19622026 0.84 THRB (0.32) THRBTHRARARBRARARARG
SCHEMBL10019896 0.83 PPARA (0.41) THRBTHRARARBRARARARG
SCHEMBL9192928 0.83 RARB (0.50) THRBTHRAMAPTSMN1; SMN2NPC1
SCHEMBL10019808 0.82 RARB (0.41) THRBTHRAMAPTRARBRARA
SCHEMBL10019365 0.82 THRB (0.43) THRBTHRAMAPTSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed