SCHEMBL10019684

SCHEMBL10019684

CCOc1ccc(OCc2ccc3c(c2F)C(F)(F)C(F)(F)c2c-3ccc(OCC)c2F)cc1F

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 16/20 0.40
PPARD Q03181 10/20 0.40
CACNA1C Q13936 1/20 0.38
KDM1A O60341 2/20 0.34
NAAA Q02083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020017 0.96 FFAR1 (0.39) FFAR1PPARDCACNA1CKDM1ANAAA
SCHEMBL10019620 0.92 CACNA1C (0.36) FFAR1PPARDCACNA1C
SCHEMBL10020013 0.90 CACNA1C (0.39) FFAR1PPARDCACNA1C
SCHEMBL10020181 0.89 CACNA1C (0.39) FFAR1PPARDCACNA1CNAAA
SCHEMBL10019621 0.87 PKM (0.34)
SCHEMBL10019660 0.87 FFAR1 (0.35) FFAR1PPARDCACNA1C
SCHEMBL10020026 0.87 CACNA1C (0.34) FFAR1PPARDCACNA1C
SCHEMBL10020119 0.85 PKM (0.34)
SCHEMBL10020003 0.84 GABRA1 (0.36) FFAR1PPARDKDM1ANAAA
SCHEMBL10020006 0.84 FFAR4 (0.35) FFAR1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed