SCHEMBL10020119

SCHEMBL10020119

CCOc1ccc(COc2ccc3c(c2F)C(F)(F)C(F)(F)c2c-3ccc(OCC)c2F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.34
MRGPRX4 Q96LA9 5/20 0.32
FGFR1 P11362 1/20 0.32
FGFR2 P21802 1/20 0.32
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
PTGER1 P34995 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019621 0.97 PKM (0.34) PKMMRGPRX4FGFR1FGFR2PTGER1
SCHEMBL10020131 0.93 CTSL (0.40) PKMCTSLCTSSCTSK
SCHEMBL10019658 0.92 CTSL (0.39) PKMCTSLCTSSCTSK
SCHEMBL10020013 0.89 CACNA1C (0.39) PKMMRGPRX4L3MBTL1
SCHEMBL10020112 0.88 CTSL (0.36) FGFR1FGFR2CTSLCTSSCTSK
SCHEMBL10020189 0.88 PKM (0.33) PKMCTSLCTSSCTSK
SCHEMBL10019629 0.87 PKM (0.32) PKMCTSLCTSSCTSK
SCHEMBL10020017 0.86 FFAR1 (0.39) PKMPDK2
SCHEMBL10020181 0.86 CACNA1C (0.39) PKMPTGER1PDK2
SCHEMBL10019684 0.85 FFAR1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed