SCHEMBL10019792

SCHEMBL10019792

C=CCCc1ccc(C(=O)Oc2ccc3c(c2F)C(F)C(F)c2c-3ccc(CCC)c2F)cc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
THRB P10828 8/20 0.35
PRSS1 P07477 1/20 0.34
ACR P10323 1/20 0.34
CTSL P07711 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
THRA P10827 5/20 0.32
CYP4A11 Q02928 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019879 0.90 MEN1 (0.32) MEN1KMT2ACYP3A4TDP1L3MBTL1
SCHEMBL10019802 0.88 KMT2A (0.36) MEN1KMT2ACYP3A4TDP1L3MBTL1
SCHEMBL10019808 0.87 RARB (0.41) MEN1KMT2ATHRBTHRACYP4A11
SCHEMBL10019880 0.87 CTSL (0.31) CTSLCTSSCTSK
SCHEMBL19622015 0.86 CTSL (0.35) CTSLCTSSCTSK
SCHEMBL10020070 0.86 CTSL (0.35) CTSLCTSSCTSK
SCHEMBL10019366 0.84 CTSL (0.35) CTSLCTSSCTSK
SCHEMBL10019941 0.84 CTSL (0.35) CTSLCTSSCTSK
SCHEMBL10019371 0.83 THRB (0.40) KMT2ATHRBCTSLCTSSCTSK
SCHEMBL10019681 0.83 CTSL (0.31) CTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed