SCHEMBL10019802

SCHEMBL10019802

C=CCCc1ccc(C(=O)Oc2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PRSS1 P07477 1/20 0.35
ACR P10323 1/20 0.35
FFAR4 Q5NUL3 1/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 3/20 0.32
THRB P10828 2/20 0.32
CCNC P24863 1/20 0.31
CDK8 P49336 1/20 0.31
CYP4A11 Q02928 1/20 0.31
GABRA1 P14867 2/20 0.31
GABRB2 P47870 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15257933 0.88 THRB (0.41) KMT2AL3MBTL1TDP1FFAR4MAPT
SCHEMBL10019792 0.88 MEN1 (0.35) KMT2AL3MBTL1MEN1CYP3A4TDP1
SCHEMBL10019895 0.88 PDE4A (0.32) KMT2AL3MBTL1MEN1CYP3A4TDP1
SCHEMBL10019877 0.86 NPC1 (0.32) KMT2AL3MBTL1MEN1CYP3A4TDP1
SCHEMBL10019363 0.86 THRB (0.35) FFAR4MAPTTHRBKDM4E
SCHEMBL10019939 0.85 GAA (0.35) KMT2AL3MBTL1MEN1CYP3A4FFAR4
SCHEMBL10019966 0.84 FFAR4 (0.36) KMT2AMEN1FFAR4GABRA1GABRB2
SCHEMBL10019806 0.84 KMT2A (0.43) KMT2AHPGDMAPTTHRBCCNC
SCHEMBL10019790 0.84 KMT2A (0.34) KMT2AL3MBTL1MEN1CYP3A4TDP1
SCHEMBL10019657 0.84 NPC1 (0.32) KMT2AMEN1FFAR4MAPTGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed