SCHEMBL10019657

SCHEMBL10019657

C=CCCc1ccc(OC(=O)c2ccc3c(c2F)C(F)C(F)c2c-3ccc(OCC)c2F)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
MAPT P10636 3/20 0.31
LMNA P02545 2/20 0.31
FFAR4 Q5NUL3 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
FFAR1 O14842 1/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
GABRA1 P14867 2/20 0.31
GABRB2 P47870 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
POLB P06746 1/20 0.30
GRK2 P25098 1/20 0.30
CASP6 P55212 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
HCRTR1 O43613 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019877 0.94 NPC1 (0.32) NPC1MAPTLMNAFFAR4KMT2A
SCHEMBL10019363 0.90 THRB (0.35) NPC1MAPTFFAR4KDM4EHCRTR1
SCHEMBL10019678 0.89 GABRA1 (0.35) NPC1MAPTLMNAFFAR4KMT2A
SCHEMBL10019681 0.88 CTSL (0.31)
SCHEMBL10019372 0.87 FFAR4 (0.31) FFAR4
SCHEMBL10019680 0.85 ESR1 (0.33) MAPTLMNAKMT2AKDM4E
SCHEMBL10020042 0.85 FFAR4 (0.31) FFAR4
SCHEMBL10019967 0.84 CALM1 (0.33) LMNAKMT2AMEN1GABRA1GABRB2
SCHEMBL10019802 0.84 KMT2A (0.36) MAPTLMNAFFAR4KMT2AMEN1
SCHEMBL10019659 0.83 KDM4E (0.41) MAPTLMNAFFAR4FFAR1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed